Diet and Gut Microbes Influence Chemotherapy Outcomes

“The first time we observed that changing the microbe or adding a single amino acid to the diet could transform an innocuous dose of the drug into a highly toxic one, we couldn’t believe our eyes,” said Eyleen O’Rourke, PhD, of UVA’s College of Arts & Sciences, the School of Medicine’s Department of Cell Biology and the Robert M. Berne Cardiovascular Research Center. “Understanding, with molecular resolution, what was going on took sieving through hundreds of microbe and host genes. The answer was an astonishingly complex network of interactions between diet, microbe, drug and host.” https://www.technologynetworks.com/drug-discovery/news/diet-and-gut-microbes-influence-chemotherapy-outcomes-335781?utm_campaign=NEWSLETTER_TN_Breaking%20Science%20News&utm_medium=email&_hsmi=89124043&_hsenc=p2ANqtz-_JlBlz4r5ze4543JQWtVmZsYUBcWBs6UcUFoXPHmeW-tHnetOOHfa-xxygtWDzA0Z9Hgqrk7JxNrsjyYaBhVio2PNWcA&utm_content=89124043&utm_source=hs_email