Researchers Discover Molecular Link That May Explain Association Between T2D And Increased Alzheimer’s Risk.

ndividuals “with type 2 diabetes have an increased risk for developing Alzheimer’s disease, and now researchers...may have discovered the molecular link that explains the association.” The investigators “focused on amyloidosis – the process by which misfolded amyloid proteins form insoluble fibril deposits – which occurs in a host of diseases, including type 2 diabetes and Alzheimer’s.” MedPage Today adds that “in transgenic mice, amyloid from the brain was found to stimulate the growth of fibrils in the pancreas, and pancreatic amyloid was also found in amyloid specific to human brain senile plaques.” The findings were published online in The American Journal of Pathology. http://www.medpagetoday.com/Endocrinology/Diabetes/50131