T2D Family History Blunts Exercise Response

t has been well-established that individuals with T2DM have reduced response to exercise, so it makes sense that the high-risk group of men in the study also had an impaired exercise response, Eckel said. Compared with individuals without a family history, they lost less weight and improved less in terms of oxygen consumption after doing the same amount of exercise, reported a research team headed by Ola Hansson, PhD, of Lund University in Malmö Sweden. Advertisement In addition, their muscle cells expressed only about half the genes associated with metabolism, oxidative phosphorylation, and cellular respiration in response to exercise compared with individuals with no family history, Hansson and colleagues reported in the Journal of Applied Physiology. http://www.medpagetoday.com/Endocrinology/Diabetes/53938?xid=nl_mpt_DHE_2015-10-07&eun=g721819d0r