Dr. House
Friday, October 21, 2016
Some NSAIDs Found To Have Greater Association With Risk Of Heart Failure.
reports, on a study published in the BMJ finding that some commonly used non-steroidal anti-inflammatory drugs (NSAIDs) are associated with higher risks of heart failure. The study found those who used NSAIDs had a 19 percent higher risk of hospital admission for heart failure. The study further found that the rate was much higher for ketorolac (83 percent), than for naproxen (16 percent), and some such as celecoxib were associated with little or no increased risk. In an accompanying editorial, Dr. Gunnar H. Gislason, chief scientific officer of the Danish Heart Foundation, wrote, “There is difference between the NSAIDs in risk of heart failure and higher dosages are associated with increased risk.” He concludes that the study shows “the elderly and patients with any heart condition should avoid NSAIDs.” The study was based on data covering 92,000 people admitted to hospitals in the Netherlands, Italy, Germany and the U.K. from 1999 to 2010. http://www.reuters.com/article/us-health-nsaids-heart-failure-idUSKCN12K2J1
I am curious as to what ingredient in some NSAIDS is doing this and how.
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