a hormone secreted by bone, called lipocalin 2 (LCN2), suppresses appetite in mice

reports new research published in Nature indicates “that a hormone secreted by bone, called lipocalin 2 (LCN2), suppresses appetite in mice.” The results indicate that LCN2 “crosses the rodents’ blood-brain barrier and binds a receptor in the hypothalamus.” Michael Krashes of the National Institute of Diabetes and Digestive and Kidney Diseases, who did not participate in the study, commented, “The big question that still remains unexplored at this point [is]: Why would something that’s secreted by the bone suppress food intake? The next step is to try and figure out why that is.” http://www.the-scientist.com/?articles.view/articleNo/48757/title/Hormone-Released-by-Bone-Suppresses-Appetite/