Cardiorespiratory Fitness Appears Not To Offset Links Between Adiposity, Certain Inflammatory Biomarkers In Older Women Who Are Physically Active

Cardiorespiratory fitness does not offset the links between adiposity and certain inflammatory biomarkers in older women who are physically active,” research indicated. The findings of the 114-woman study were published online in the Journal of Clinical Endocrinology & Metabolism. The results emphasize the need for reducing abdominal adipose tissue in older adults, regardless of cardiorespiratory fitness. The study included older community-dwelling women aged 65 to 70 years who were free from heart disease and diabetes (n = 114). Women were required to be engaged in 150 min/wk of moderate to vigorous physical activity to be eligible for inclusion. Researchers used a standardized submaximal test with a cycle ergometer to assess cardiorespiratory fitness. They categorized participants into high or low adiposity-related metabolic risk groups based on measures of body mass index, waist-to-hip ratio, and total fat mass. They also analyzed inflammatory and metabolic biomarkers including high sensitivity C-reactive protein, interleukin-6 (IL-6), IL-10, IL-18, adiponectin, monocyte chemoattractant protein-1, and macrophage inflammatory protein alpha. The results indicated that participants in the high-risk metabolic group had significantly elevated C-reactive protein levels, lower adiponectin levels, and higher inflammatory scores compared with participants in the low-risk group, regardless of adiposity measures (P <.05). https://www.endocrinologyadvisor.com/home/topics/obesity/cardiorespiratory-fitness-does-not-offset-inflammatory-risks-of-adiposity/