Dr. House

Dr. House
Dr. House

Tuesday, October 31, 2017

Risk For Death May Be Elevated For Women With Infertility Issues,

reports that research suggests that “for women with infertility issues, the risk for death is elevated, especially from breast cancer and diabetes.” Investigators found that “after parity, socioeconomic risk factors, and underlying comorbidities were controlled for, risk for death during the 13-year follow-up period was 10% higher in women with infertility issues than without.” The findings were presented at the American Society for Reproductive Medicine 2017 Scientific Congress. https://login.medscape.com/login/sso/getlogin?urlCache=aHR0cHM6Ly93d3cubWVkc2NhcGUuY29tL3ZpZXdhcnRpY2xlLzg4Nzc3Mg==&ac=401

Patients With Type 1 Diabetes And Those With Type 2 Diabetes May Have Different Depression Profiles

reports that “patients with type 1 diabetes (T1D) and patients with type 2 diabetes (T2D) had very different profiles of depression,” researchers concluded. In fact, the study revealed that “patients with T2D had traits of atypical depression, whereas those with T1D and depression exhibited traits of melancholia.” Included in the study were 24 patients with T2D and 148 patients with T1D. The findings were published online Sept. 20 in BMC Psychiatry. http://www.endocrinologyadvisor.com/type-2-diabetes/types-of-depression-in-type-1-diabetes-vs-type-2-diabetes/article/703295/

FDA Issues Warning About Black Licorice For Halloween

As the video explains, the cuplrit is a substance in black licorice named glycyrrhizin, which, in addition to being tricky to pronounce when your mouth is full of black licorice, may result in a decrease in potassium levels in your body. Drops in potassium levels can lead to abnormal heart rhythms, high blood pressure, muscle weakness, swelling, and even heart failure. The risk is particularly higher if you are over 40 years old and eat more than 2 ounces of black licorice a day for at least two weeks, as indicated by the United Kingdom's National Health Service. But this does not mean if you are 39 years and 364 days old you are in the clear. Eating large amounts of black licorice may be risky for younger folks as well. https://www.forbes.com/sites/brucelee/2017/10/31/fda-issues-warning-about-black-licorice-for-halloween/#2f2513f75ff3

Monday, October 30, 2017

FREE community awareness event: FIGHTING THE OPIOID EPIDEMIC Nov 15 Fairborn, OH

FIGHTING THE OPIOID EPIDEMIC The Hondros College of Nursing, Fairborn campus is hosting an important and timely community event about the opioid drug problem and how nurses can make a positive difference. Fighting the Opioid Epidemic: How Nurses Can Help will take place on Wednesday, Nov. 15 from 11am – 2:30pm at the Fairborn campus. This event is free and open to the public. Hondros College of Nursing 1810 Successful Drive Fairborn, OH 45324

Opioid Scripts: Is the ER a Primary Source? Emergency docs: Don't blame us

https://www.medpagetoday.com/PainManagement/Opioids/68869?xid=NL_breakingnews_2017-10-30&eun=g721819d0r

Friday, October 27, 2017

Mineral And Bone Disorder Biomarkers May Be Linked With Estimated Glomerular Filtration Rate, Risk For Infection,

reports, “Mineral and bone disorder biomarkers were linked with estimated glomerular filtration rate and risk for infection,” researchers concluded after conducting “a community-based cohort study of 11,218 adults from the Atherosclerosis Risk in Communities (ARIC) study, which enrolled patients aged 45 to 64 years between 1987 and 1989.” The findings were published online in the Journal of Clinical Endocrinology & Metabolism. https://www.healio.com/endocrinology/bone-mineral-metabolism/news/in-the-journals/%7Baaa10c3c-2569-4ce4-9792-f636c700e793%7D/mineral-bone-metabolism-play-role-in-infection-etiology

People Carrying Obesity Genes May Tend To Gain More Weight If They Do Not Work Out Or Do Not Get Enough Sleep

“People carrying so-called ‘obesity’ genes tend to gain more weight if they don’t work out or don’t get enough sleep,” researchers found after tracking “physical activity and sleep patterns for about 85,000 people in England, aged 40 to 70,” then computing “a genetic risk score for each person based on 76 common variants known to be associated with increased risk for obesity.” The findings were presented at the annual meeting of the American Society of Human Genetics. https://consumer.healthday.com/vitamins-and-nutrition-information-27/obesity-health-news-505/when-it-comes-to-obesity-genes-just-partly-to-blame-727739.html

Thursday, October 26, 2017

Triclosan 6 Appears To Accumulate In Toothbrushes Over Time.

“The researchers say that the FDA does not consider mouth exposure to triclosan toothpastes to be a health risk.” Currently, the chemical “is found in toothpastes that are marketed as antibacterial, and Colgate is currently the only brand that makes toothpaste that contains triclosan.” Should people “want to avoid triclosan while brushing their teeth, the researchers recommend changing to a toothpaste without triclosan and buying a new toothbrush.” http://time.com/4995690/triclosan-toothpaste/

Eating Alone May Be Linked To Higher Risk Of Metabolic Syndrome In Some People

reports that research suggests “people who eat most of their meals alone may be at increased risk for heart disease and diabetes.” Investigators “found that men who dined solo at least twice a day were more likely to have metabolic syndrome...compared to those who always dined with others.” The findings were published in Obesity Research & Clinical Practice. http://time.com/4995466/eating-alone-metabolic-syndrome/

Being Underweight In Early Or Mid-Adulthood May Increase Risk For Early Menopause,

“Women who were underweight in early or mid-adulthood had a higher risk for early menopause,” researchers concluded after analyzing “data from the Nurses’ Health Study.” In fact, “women who were underweight at age 18 had more than 50% higher risk for early menopause, compared with those of normal weight,” while “women who were underweight at 35 had nearly 60% higher risk.” The findings were published online in the journal Human Reproduction. https://www.medpagetoday.com/endocrinology/menopause/68791

Researchers Say Type 3c Diabetes May Be More Common Than Previously Thought.

“Type 3c diabetes, which occurs after a trauma to the pancreas, requires a stronger medical intervention than Type 2 – making a misdiagnosis particularly dangerous.” A corresponding author on the study wrote, “People with Type 3c diabetes were twice as likely to have poor blood sugar control than those with Type 2 diabetes.” In addition, they are “five to ten times more likely to need insulin, depending on their type of pancreas disease.” reports UK researchers “say Type 3c diabetes may be more common than previously thought, saying some people with Type 2 may have been misdiagnosed.” In research published online in Diabetes Care, the study authors “found that about 1.5% of 31,789 new cases of diabetes over a 10 year period were diagnosed as Type 2 instead of Type 3c.” According to the Daily News, “a National Institutes of Health study from 2008 also identified Type 3c as an underdiagnosed form of diabetes, but still many people aren’t aware of it.” https://www.washingtontimes.com/news/2017/oct/25/diabetes-type-3c-misdiagnosed-majority-patients/

Wednesday, October 25, 2017

A Weed Killer Is Increasingly Showing Up in People's Bodies

reports that glyphosate is pervasive in European soil and people, “but environmentalists claim that glyphosate is so non-selective that it can even kill large trees and is destructive to wild and semi-natural habitats, and to biodiversity.” Many people are also concerned that the chemical could be toxic to humans because the IARC concluded in 2015 that it is “probably carcinogenic.” Researchers “used data from the long-running and influential Rancho Bernardo Study of Healthy Aging, established in 1972.” The article notes that glyphosate is the active ingredient in Monsanto’s herbicide product Roundup, and there is an ongoing controversy concerning whether or not the chemical is a carcinogen. http://time.com/4993877/weed-killer-roundup-levels-humans/

Dementia Less Likely With Oral Anticoagulants for Afib Similar effect observed with NOACs, warfarin in Swedish registry data

https://www.medpagetoday.com/Cardiology/Arrhythmias/68774?xid=NL_breakingnews_2017-10-25&eun=g721819d0r

Tuesday, October 24, 2017

Advertisement Fewer People Have Undiagnosed Diabetes Than Previously Estimated,

reports a study published in the Annals of Internal Medicine found that in using the American Diabetes Association’s (ADA) criteria for diagnosing diabetes, there were an estimated 25.5 million people with diabetes in 2015 with about 11 percent of them undiagnosed. The previous, “less stringent standard to data from the National Health and Nutrition Examination Survey and the U.S. Census” used by the CDC led to an estimate of 33.3 million people with diabetes and nearly 24 percent of whom were undiagnosed. http://www.npr.org/sections/health-shots/2017/10/23/559486787/screening-for-diabetes-is-working-better-than-thought

Data Show Americans Retiring Later, Dying Sooner, And In Poorer Health.

reports that data released last week suggests that Americans are retiring later, dying sooner, and suffer more serious health problems in their late 50s. The data by the Society of Actuaries show that nearly one-third of those age 65 to 69 are still working and age-adjusted mortality rates rose 1.2 percent from 2014-2015. By the age of 58 to 60, a quarter of Americans rated their health as “poor” or “fair.” The article mentions several potential causes for why Americans’ health appears to be getting worse, including a suicide epidemic, drug and alcohol abuse, and higher obesity rates. https://www.bloomberg.com/news/articles/2017-10-23/americans-are-retiring-later-dying-sooner-and-sicker-in-between

Probiotic Supplementation May Benefit Overweight Or Obese Adults,

“Adults with overweight or obesity who used a probiotic supplement experienced greater reductions in weight, BMI, fat mass and fat percentage compared with those who took a placebo,” researchers found in a 15-study analysis including data on 957 obese or overweight adults. The findings were published online in Obesity Reviews. https://www.healio.com/endocrinology/obesity/news/in-the-journals/%7B49730cdc-5051-43d4-b1ab-76facf2507cc%7D/short-term-probiotic-supplementation-may-aid-weight-loss

Vitamin D And Calcium May Not Reduce Fracture Risk In Adults When Taken As A Preventive Measure, USPSTF Finds.

“Vitamin D and calcium may not reduce the risk of fractures in adults when taken as a “preventive measure, the US Preventive Services Task Force (USPSTF) concluded. The findings can be seen here. http://www.endocrinologyadvisor.com/bone-metabolism/vitamin-d-calcium-supplements-fracture-risk/article/701834/

Statin Use May Increase Risk Of Type 2 Diabetes Among High-Risk Individuals

reports a study published in BMJ Open Diabetes Research & Care found that long-term use of statins “is associated with an increased risk of type 2 diabetes of approximately 30% in individuals at high-risk of the disease, even after taking into account known risk factors and potential confounders.” Researchers reached this conclusion after examining more than 3,200 participants in the Diabetes Prevention Program (DPP) over 10 years, finding that “statin use was linked to a 36% increased risk of being diagnosed with type 2 diabetes.” https://login.medscape.com/login/sso/getlogin?urlCache=aHR0cHM6Ly93d3cubWVkc2NhcGUuY29tL3ZpZXdhcnRpY2xlLzg4NzQ3Mg==&ac=401

Monday, October 23, 2017

Obesity Leads To Release Of Cytokines Into The Bloodstream Which Impact Breast Cancer Cell Metabolism,

Obesity leads to the release of cytokines into the bloodstream which impact the metabolism of breast cancer cells, making them more aggressive as a result,” researchers found in a study published online in Cell Metabolism. https://endocrinenews.endocrine.org/researchers-report-obesity-promotes-breast-cancer/

Friday, October 20, 2017

Men With Prolactinoma May Be At Higher Risk For Incident Cardiovascular Disease.

“Men with prolactinoma are at higher risk for incident cardiovascular disease compared with women with prolactinoma and healthy men and women,” researchers concluded after evaluating data on “2,233 adults with prolactinoma (1,822 women) and 10,355 matched controls (8,557 women).” The findings were published online in Clinical Endocrinology. https://www.healio.com/endocrinology/neuroendocrinology/news/in-the-journals/%7B704c9691-4570-4039-ae23-a8ceb30166e6%7D/prolactinoma-increases-cvd-risk-in-men

Scientists Identify And Improve Protein That Causes Weight Loss And Improves Health In Obese Mice And Monkeys.

reports scientists “report they have identified and improved upon a naturally occurring protein that brought about significant changes in obese mice and monkeys, including weight loss and rapid improvements on measures of metabolic and heart health.” The findings were published in Science Translational Medicine. http://www.latimes.com/science/sciencenow/la-sci-sn-weight-loss-protein-20171019-story.html

Thursday, October 19, 2017

Do Obesity and Depression Have Immunometabolic Ties? Disorders may share pathophysiologic mechanisms

The shared pathophysiologic mechanisms may include immunometabolic pathways characterized by an increased pro-inflammatory response and the dysregulation of hormones responsible for energy metabolism. "Obesity is characterized by low-grade pro-inflammatory activation. Peripheral immune activation could trigger brain inflammatory responses participating in depressive neurochemical and/or endocrine processes (i.e., depletion and degradation of tryptophan toward neurotoxic end products or hyperactivation of the hypothalamic-pituitary-adrenal axis)," they wrote. https://www.medpagetoday.com/endocrinology/obesity/68627

Obesity Found To Be A Risk Factor For 30-Day Readmission Among Young Children Recently Hospitalized For Asthma.

reports that research indicated “obesity was...a risk factor for 30-day readmission among young children recently hospitalized for asthma.” In the “study of more than 38,000 children living in Japan, obese patients were more likely to be older, male, and have pre-existing comorbidities.” Additionally, “they...showed significantly higher 30-day readmission (adjusted odds ratio 1.26, 95% CI 1.03-1.54) and longer length of stay (adjusted difference 0.12 days, 95% CI 0.10- 0.20 days) than the children whose weight was classified as normal.” The findings were published in Pediatric Allergy and Immunology. https://www.medpagetoday.com/pediatrics/asthma/68638

Women With Type 2 Diabetes Who Receive Long-Acting Insulin Glargine May Have Increased Risk Of Breast Cancer,

reports that researchers found that “women with type 2 diabetes who received long-acting insulin glargine...had a 1.4-fold increased risk of breast cancer compared with women who were given intermediate-acting neutral protamine Hagedorn (NPH) insulin during roughly 4 years and up to 12 years of follow-up.” However, individuals “who received insulin detemir...did not have any increased risk of breast cancer.” Medscape adds that “of note, the breast-cancer signal with insulin glargine was only significant among prior insulin users and not new users.” https://login.medscape.com/login/sso/getlogin?urlCache=aHR0cHM6Ly93d3cubWVkc2NhcGUuY29tL3ZpZXdhcnRpY2xlLzg4NzIwNA==&ac=401

Wednesday, October 18, 2017

Study Reveals Association Between Depression, Sagging Testosterone Levels In New Fathers.

reports research indicates that postpartum depression “may occur in from 7 percent to 10 percent of new fathers, compared to about 12 percent of new mothers, and that depressed dads were more likely to spank their children and less likely to read to them.” Now, research published in Hormones and Behavior “has found a link between depression and sagging testosterone levels in new dads, adding physiological weight to the argument that postpartum depression isn’t just for women anymore.” In addition, the study revealed that “while high testosterone levels in new dads helped protect against depression in fathers, it correlated with an increased risk of depression in new moms.” https://www.nytimes.com/2017/10/17/well/family/can-fathers-have-postpartum-depression.html

Health Experts Call For Changes To Food Environment As CDC Research Shows Rising Obesity Rates.

With obesity rates in the US at “a new high,” public health experts are calling for “an aggressive shift in strategy – one that would change the food environment through initiatives such as soda taxes,” USA Today (10/17, Toy) reports. Traditional “public health efforts have centered on communicating messages about what is healthy in the hopes of changing people’s behavior,” but new research by the Centers for Disease Control and Prevention’s National Center for Health Statistics shows a steady increase in obesity rates among US adults, up from 30.5 percent in 1999-2000 to 39.8 percent in 2015-2016. The article cites “Craig Hales, the study’s lead researcher and a medical epidemiologist at the CDC,” and notes that “physician Jerome Adams, who was sworn in as surgeon general in August, on Monday cited obesity as among the Department of Health and Human Services’...top priorities.” https://www.usatoday.com/story/news/2017/10/17/obesity-rates-skyrochave-hit-new-high-and-health-experts-say-its-time-change-how-were-dealing-proble/773015001/

Tuesday, October 17, 2017

Shingles Seen as Possible Trigger for Cardiovascular Events Younger age associated with increased risk; but biological mechanism unclear

https://www.medpagetoday.com/Cardiology/MyocardialInfarction/66384?xid=nl_mpt_DHE_2017-10-17&eun=g721819d0r&pos=3

NIH To Launch Male Contraceptive Study.

reports the National Institutes of Health will start recruiting couples for a clinical trial of a male contraceptive gel that is applied to men’s shoulders. The gel contains the hormone progestin, which limits the testes from generating testosterone at a level that supports sperm production. A male contraceptive clinical trial several years ago ended early after some participants experienced depression and mood disorders. The NIH trial is expected to take three years, and if successful, researchers would begin another trial. However, even if the trial produces results, researchers say no pharmaceutical company is willing to manufacture the gel. https://www.wsj.com/articles/the-search-for-a-new-form-of-birth-control-1508173537

Monday, October 16, 2017

Vaginal Estrogen Use Safe Among Postmenopausal Women,

reported that in a study, “vaginal estrogen use was found to be safe among postmenopausal women.” Investigators “found vaginal estrogen use was not associated with any increased risk for a global index event.” MedPage Today added that the “findings were similar among users with an intact uterus (HR 0.63, 95% CI 0.51-0.77) or who have undergone a hysterectomy (HR 0.83, 95% CI 0.63-1.08) after adjustment for age, education, prior estrogen use, and a history of cancer, CVD, or DVP/PE.” The findings were presented at the annual meeting of the North American Menopause Society. https://www.medpagetoday.com/meetingcoverage/nams/68526

Friday, October 13, 2017

High Resolution Rate in Viral Conjunctivitis Almost 80% of patients virus free by day 6

Almost a third of patients with adenoviral conjunctivitis had clinical resolution within 6 days when treated with dexamethasone/povidone-iodine ophthalmic suspension (SHP640) and almost 80% had viral eradication, according to a randomized trial reported here. Virus eradication occurred as early as 3 days among patients treated with povidone-iodine, with or without dexamethasone. Treatment-emergent adverse events occurred more often with SHP640 compared with a vehicle solution administered to a control group, Abhijit Narvekar, MBBS, DPM, of Shire Pharmaceuticals in Lexington Massachusetts, reported at the American Academy of Optometry (AAOpt) meeting here. "No medications are currently approved in the U.S. for adenoviral conjunctivitis, and infected patients can easily transmit the disease to others," Narvekar said at an AAOpt press briefing. https://www.medpagetoday.com/MeetingCoverage/AAOPT/68512?xid=nl_mpt_DHE_2017-10-13&eun=g721819d0r&pos=3

Nearly Four In 10 US Adults Are Obese, CDC Statistics Show.

reports that data released Friday by the CDC show that in 2015 and 2016, nearly “4 in 10 American adults had a body mass index that put them in obese territory.” The piece suggests that “the report underscores a continuing pattern of racial and ethnic disparities when it comes to weight,” pointing out that “obesity rates among African Americans and Latinos have been consistently higher than those seen in whites, and the new survey shows no change in that pattern.” http://www.latimes.com/science/sciencenow/la-sci-sn-obesity-rates-us-20171012-story.html

Wednesday, October 11, 2017

Smoking Raises Risk for Seropositive SLE Risk with current smoking increased twofold

https://www.medpagetoday.com/Rheumatology/Lupus/68450?xid=nl_mpt_DHE_2017-10-11&eun=g721819d0r&pos=1

Number Of Obese Children Has Increased More Than Tenfold In The Past Four Decades,

reports research published online in The Lancet reveals that “the number of obese children has increased more than tenfold in the past four decades – from five million girls in 1975 to 50 million in 2016, and from six million boys in 1975 to 74 million in 2016.” In fact, “one in every five children on the planet is either obese...or overweight,” the study involving data “on nearly 129 million children ages five to 19 in 200 countries” reveals. https://mail.google.com/_/scs/mail-static/_/js/k=gmail.main.en.khUFNOKniXg.O/m=pds,pdl,pdit,m_i,pdt,t,it/am=ccE8IN8PAS4zYFylCYTZ__nLpeHB3m___x9AQgXwDfhv7iPw4wAAAAAAAAAAAAAAAAAAAEALik8/rt=h/d=1/rs=AHGWq9DR-IEhS3OgCxBWwxmd6PC9GJsvtQ

Tuesday, October 10, 2017

Parasite Plagues Subset of Iraq War Vets Latent visceral leishmaniasis can cause serious health issues

U.S. service members deployed to Iraq showed sign of having been infected with latent visceral leishmaniasis (VL) during their service, researchers said here. In one study, latent VL was identified in asymptomatic Operation Iraqi Freedom soldiers (10.2% of 88), potentially putting them at risk of activation of the disease if they're immunosuppressed, according to Edgie-Mark Co, DO, PhD, of the William Beaumont Army Medical Center in El Paso, Texas. In another study, 20 veterans with asymptomatic latent VL had no active disease, although it was not clear how likely the condition was to resurface and cause serious health problems, reported Nate Copeland, MD, of the Clinical Trials Center at Walter Reed Army Institute in Bethesda, Maryland, and https://www.medpagetoday.com/MeetingCoverage/IDWeek/68416?xid=nl_mpt_DHE_2017-10-10&eun=g721819d0r&pos=3

Antibiotic Use In First Four Years Of Childhood Not Associated With T1D, Celiac Disease

“Within the first four years of life, exposure to commonly prescribed antibiotics for children – cephalosporins, penicillins, and macrolides – was not associated with autoimmunity development for celiac disease and type 1 diabetes [T1D],” researchers found. The findings of the 8,495-child study were published online in https://www.medpagetoday.com/endocrinology/type1diabetes/68413

Women Who Consume Foods With A Higher Dietary Acid Load May Be More Likely To Develop Gestational Diabetes,

reports, “Women who consume foods with a higher dietary acid load are more likely to develop gestational diabetes when compared with women who consume a lower dietary acid load,” researchers concluded after analyzing “data from 263 healthy pregnant women and 200 pregnant women with gestational diabetes between five and 28 weeks’ gestation,” then adjusting for confounding factors. The findings were published online in Clinical Nutrition. https://www.healio.com/endocrinology/diabetes/news/in-the-journals/%7Bb7093e19-8ca2-4b7e-a745-cdc961f54554%7D/higher-dietary-acid-load-increases-gestational-diabetes-risk?nc=1

Vitamin D And Calcium From Food, But Not Supplements, May Be Linked To Reduced Risk For Early Menopause,

reported that research suggests “vitamin D and calcium from food, but not supplements, were associated with a decreased risk for early menopause, and the hormones in dairy food may partly explain why.” Investigators found that “compared with women with the least amount of vitamin D in their diet, those with the most were 17% less likely to undergo menopause before the age of 45.” But, “compared with women who did not take vitamin D supplements, those who took the recommended daily allowance of 600 IUs or more had no significant change in risk.” The findings were published online in the American Journal of Clinical Nutrition. https://www.medpagetoday.com/clinicalfocus/osteoporosis/68303

Does Fat Intake Play a Role in Pediatric MS Relapse? Observational study offers some evidence of association, not causality

https://www.medpagetoday.com/Neurology/MultipleSclerosis/68437?xid=NL_breakingnews_2017-10-10&eun=g721819d0r

Saturday, October 7, 2017

Fungal Superbug' Raising Fears But few Candida auris cases so far in U.S.

Even when the fungus, Candida auris, is not completely resistant to the available antifungal drugs, it can be a challenge, Chiller told a symposium here at the annual IDWeek meeting, sponsored jointly by the Infectious Diseases Society of American (IDSA), the Pediatric Infectious Diseases Society (PIDS), the Society for Healthcare Epidemiology of America (SHEA), and the HIV Medicine Association (HIVMA). The fungus, first reported in 2009 and since seen around the world, is readily transmitted since it colonizes both the skin and the environment, but is not easily identified or treated. And like other Candida species, it can cause severe invasive disease and death. Candidemia is already the most common bloodstream infection in the U.S., Chiller said, with a 30% mortality rate. But it has usually been thought of as an "autoinfection https://www.medpagetoday.com/MeetingCoverage/IDWeek/68343?xid=nl_mpt_DHE_2017-10-06&eun=g721819d0r&pos=1

Kids' Experiment Shows Value of Washing Hands Side benefit: less absenteeism from school

https://www.medpagetoday.com/MeetingCoverage/IDWeek/68353?xid=nl_mpt_DHE_2017-10-06&eun=g721819d0r&pos=0

Antibiotic Pipeline Overflows New drugs and new classes intrigue IDWeek audience

"We have new drugs for bad bugs," quipped co-moderator Cesar Arias, MD, PhD, of the University of Texas Medical School at Houston. The new drugs include beta-lactamase inhibitors, a cephalosporin, an aminoglycoside, a fluoroquinolone, and a tetracycline, as well as several first-in-class medications. Themes that emerged during the discussion were twofold: The new drugs in established classes aim to overcome some of the safety issues of their predecessors And the approach to resistance is much more nuanced than it has been in the past, so that doctors will soon be able to choose medications that target specific mechanisms of resistance Already available is delafloxacin (Baxdela), a new fluoroquinolone that won FDA approval in June for acute bacterial skin and skin structure infections (ABSSSI), according to Sue Cammarata https://www.medpagetoday.com/MeetingCoverage/IDWeek/68389?xid=nl_mpt_DHE_2017-10-07&eun=g721819d0r&pos=0

Wednesday, October 4, 2017

Excess Body Fat Linked To Increased Risk For At Least 13 Different Types Of Cancer, Study Indicates.

A new report from the U.S. Centers for Disease Control and Prevention (CDC)” indicates that “being overweight puts a person at significantly higher risk for cancer.” The study “published in Vital Signs,” which is “based on data from the 2014 United States Cancer Statistics, finds excess body fat increases the risk for at least 13 different types of cancer.” The investigators “found that although the overall rate of new cancer diagnoses has decreased since the 1990s, cancers” linked to “being overweight or obese have dramatically increased.” http://www.newsweek.com/cdc-report-links-13-cancers-high-bmi-overweight-obesity-676764

Tuesday, October 3, 2017

In RA, Only Remission Staves Off Infection Serious infections were 69% higher with low disease activity

https://www.medpagetoday.com/Rheumatology/Arthritis/68241?xid=nl_mpt_DHE_2017-10-02&eun=g721819d0r&pos=1

Patients With T2D Who Take Metformin For Many Years May Be More Likely To Develop Anemia,

“People with type 2 diabetes who take metformin for many years are more likely to develop anemia than are those who do not,” researchers concluded in a poster presentation at the annual meeting of the European Association for the Study of Diabetes. When interviewed, the study’s lead author said, “The Diabetes Prevention Program (DPP) study showed that long-term metformin use in individuals with impaired glucose tolerance was associated with an increased risk of anemia, and this was independent of vitamin B12 status.” That particular study was published last year in the Journal of Clinical Endocrinology & Metabolism. http://www.mdedge.com/clinicalendocrinologynews/article/148450/anemia/many-years-metformin-linked-anemia-risk

Monday, October 2, 2017

FDA Proposes Giving Food Manufacturers More Time To Comply With New Nutrition Label Requirements.

reported the Food and Drug Administration “proposed giving manufacturers an extra 1-1/2 years to comply with new nutrition label requirements on packaged foods.” Under the proposal, the agency would give “big companies, defined as those with more than $10 million in annual sales, to Jan. 1, 2020, while smaller companies [would] have until Jan. 1, 2021 to comply.” http://www.reuters.com/article/us-usa-nutrition-fda/fda-proposes-1-1-2-year-delay-to-nutrition-label-changes-idUSKCN1C42FA