Dr. House

Dr. House
Dr. House

Wednesday, February 28, 2018

Local whooping cough cases reported, vaccine encouraged

http://www.examiner.org/news/93519-local-whooping-cough-cases-reported-vaccine-encouraged

Graves Disease Explained.

reports that the autoimmune thyroid disorder known as “Graves’ disease affects approximately one in 200 people, according to the National Institutes of Health, and it occurs much more often in women than men.” Endocrine Society Past President Leonard Wartofsky, MD, an endocrinologist, explained, “There are effects on virtually every tissue in the body, every organ, every system. .. The thyroid is important for heart, kidney, and muscle function, but in the case of hyperthyroidism it’s excessive.” The article goes on to explain theories of what causes the disease, its symptoms, how it is diagnosed, and how it is treated. http://www.goodhousekeeping.com/health/news/a47975/what-is-graves-disease/?src=socialflowTW

Tuesday, February 27, 2018

Testosterone Injections May Be Linked To Increased Risk For Cardiovascular Events In Older Men,

So if you read my other post about testosterone reducing frailty, then see this article, it makes you opt out of treatment. reports that research indicated “men aged at least 65 years receiving testosterone injections had an increased risk for cardiovascular events, including myocardial infarction, stroke or unstable angina, within 7 days of administration.” However, “the risk was not increased in younger men.” The findings were published in Clinical Endocrinology. https://www.healio.com/endocrinology/hormone-therapy/news/in-the-journals/%7B25f37120-9443-4977-b4ab-824498ba3de9%7D/testosterone-injection-in-older-men-increases-cv-risk

Asthma In Women May Be Linked To Changes In Levels Of Female Hormones,

reports that research suggests “there may be a link between asthma in women and changes in levels of female hormones such as estrogen and progesterone.” Investigators “reviewed more than 50 studies of more than 500,000 women with asthma from puberty to age 75.” The researchers “found that starting to have periods before age 11 and having irregular periods were associated with a higher risk of asthma.” The findings were published in the Journal of Allergy and Clinical Immunology. https://consumer.healthday.com/respiratory-and-allergy-information-2/asthma-news-47/female-hormones-may-play-part-in-asthma-731207.html

Research Offers More Evidence Of Association Between Lower Free Testosterone Levels And Higher Levels Of Frailty In Older Men.

reports that research “provides more evidence of a link between lower free testosterone levels and higher levels of frailty in older men.” However, “a researcher says proof of a causal connection remains elusive.” In an interview, lead author Agnieszka Swiecicka, MD, said, “Our study demonstrates clear associations between testosterone and frailty progression, and, although causality and directionality of the hormone/frailty relationships require clarification, the results presented here make a strong case for large interventional trials of testosterone therapy in frail men to determine whether such treatment would be beneficial.” The findings were published in the Journal of Clinical Endocrinology and Metabolism. https://www.mdedge.com/clinicalendocrinologynews/article/159488/mens-health/free-testosterone-linked-frailty-older-men

No Link Found Between Progestin-Only Hormonal Contraception And Depression, Meta-Analysis Reveals.

reports that a 26-study meta-analysis published online Feb. 26 in the journal Contraception “found no link between certain types of birth control and depression.” http://time.com/5172964/does-birth-control-cause-depression/

Monday, February 26, 2018

Startups Analyzing Gut Bacteria To Refine Diets.

reports that startup companies are using the sequencing data of gastrointestinal bacteria to help people diet more effectively. Israel-based DayTwo Inc. and Viome Inc., a company backed by Silicon Valley entrepreneur Naveen Jain, say they can help people normalize their blood sugar by analyzing the mix of bacteria that influence their glucose response. Until now, most diets have been based on the glycemic index, a half-century-old list that ranks foods based on how they affect blood sugar. https://www.wsj.com/articles/dietary-advice-based-on-the-bacteria-in-your-gut-1519614301

Many Skin-Lightening Creams Contain Harmful Chemicals.

reports that many skin-lightening products contain chemicals that can be harmful, such as mercury or hydroquinone. The article explains that the Food and Drug Administration “classifies skin whitening creams as both a cosmetic and a drug,” and FDA spokesperson Peter Cassell said that mercury has been prohibited in cosmetics since 1973. https://www.npr.org/2018/02/25/588632658/you-have-dark-skin-and-you-are-beautiful-the-long-fight-against-skin-bleaching

Wine Consumption May Be Linked To Healthier Arteries For Certain People With Diabetes

reported that research suggests some individuals with diabetes who have “plaque buildup in their arteries might have less debris in these blood vessels after adding wine to their diets.” The study, which used ultrasound, was published in the European Journal of Clinical Nutrition. https://www.reuters.com/article/us-health-arteries-wine/wine-tied-to-healthier-arteries-for-some-diabetics-idUSKCN1G72P8

FDA Says Study Found BPA Unlikely To Be Dangerous To Human Health.

On its website, NBC News (2/25, Fox) reports the FDA announced Friday that a new study by the National Toxicology Program suggests the chemical known as bisphenol A, or BPA, “is unlikely to be harmful to people in the doses usually seen.” Dr. Stephen Ostroff, an FDA deputy commissioner, explained, “Overall, the study found ‘minimal effects’ for the BPA-dosed groups of rodents. ... Our initial review supports our determination that currently authorized uses of BPA continue to be safe for consumers.” NBC says, “The report covers years of testing BPA in many different groups of rats for two years.” https://www.nbcnews.com/health/health-news/bpa-unlikely-be-harmful-federal-study-shows-n850826?cid=public-rss_20180223

Friday, February 23, 2018

CDC: 22 More Kids Die from Flu-Related Causes But other flu indicators ticked down from last week

https://www.medpagetoday.com/infectiousdisease/uritheflu/71208?xid=nl_mpt_DHE_2018-02-17&eun=g721819d0r&pos=1&utm_source=Sailthru&utm_medium=email&utm_campaign=Daily%20Headlines%202018-02-17&utm_term=Daily%20Headlines%20-%20Active%20User%20-%20180%20days

More Women Aged 40 And Older Having Children,

reports new data suggest the birthrate in the US reached a new low in 2017; however, “among women over 40, the birthrate has increased” with women aged 40 to 44 having a four percent increase in birthrate and women aged 45 to 49 having a .1 percent increase. According to Dr. Norbert Gleicher of the Center for Human Reproduction, “This would have been unimaginable 10 years ago.” http://abcnews.go.com/GMA/Wellness/women-babies-50/story?id=52971244

Presence Of Microbiota In The Infant Gut Appears To Mediate The Link Between Maternal And Child Overweight Status, Particularly In Cesarean-Delivered Babies

“Babies born to overweight or obese mothers, either vaginally or via cesarean section, are more likely to become overweight or obese than those born vaginally to normal-weight mothers,” researchers found. And, “in addition to mode of birth, the presence of microbiota in the infant gut appears to mediate the link between maternal and child overweight status, particularly in cesarean-delivered babies,” the study revealed. The findings were published online in JAMA Pediatrics. The authors of an accompanying editorial observed, “The current study adds important information supporting the interdependency of maternal weight status and mode of delivery in forming the ‘microbial communities of early life,’ which are linked to offspring weight status.” https://jamanetwork.com/journals/jamapediatrics/article-abstract/2672735

When IBS Overlaps with IBD Inflammatory bowel disease patients in remission but with persistent symptoms respond well to therapies for irritable bowel syndrome

https://www.medpagetoday.com/reading-room/aga/lower-gi/71308?xid=nl_mpt_DHE_2018-02-23&eun=g721819d0r&pos=1&utm_source=Sailthru&utm_medium=email&utm_campaign=Daily%20Headlines%202018-02-23&utm_term=Daily%20Headlines%20-%20Active%20User%20-%20180%20days

Thursday, February 22, 2018

Prolonged Opioid Use Common After Bariatric Surgery

reports in a news roundup that nearly “25% of bariatric surgery patients reported taking opioids a year after the procedure, according to a recent analysis” published in Gastroenterology and Endoscopy News. https://www.medpagetoday.com/gastroenterology/generalgastroenterology/71290

ACIP Reinstates FluMist for 2018-2019 Flu Season Committee persuaded by new efficacy analyses

After a 2-year absence, FluMist is back on the 2018-2019 influenza vaccine schedule, following a vote from the CDC Advisory Committee on Immunization Practices (ACIP) here. The panel also gave a unanimous endorsement to the Heplisav-B vaccine against hepatitis B virus. ACIP members voted 12-2 to include the live attenuated influenza vaccine (LAIV) as "an option for influenza vaccination for persons for whom it is appropriate" in the 2018-2019 influenza season. An additional motion to give a preferential recommendation to the inactivated influenza vaccine (IIV) and recombinant influenza vaccine (RIV) over LAIV was voted down 3-11. The vaccine was also added back to the Vaccines for Children (VFC) program in a 14-0 vote. What changed their minds? CDC research from prior studies of live attenuated influenza vaccine showed that effectiveness of LAIV was 45% against influenza A and B, with 25% protection against influenza A (H1N1)pdm09 compared with unvaccinated children. CDC researchers also found that while inactivated influenza vaccine was "better" in all age groups against influenza A(H1N1)pdm09, compared with LAIV, there was no statistically significant difference in protection between the two vaccines for influenza A (H3N2) and influenza B viruses. https://www.medpagetoday.com/meetingcoverage/acip/71298?xid=nl_mpt_DHE_2018-02-22&eun=g721819d0r&pos=0&utm_source=Sailthru&utm_medium=email&utm_campaign=Daily%20Headlines%202018-02-22&utm_term=Daily%20Headlines%20-%20Active%20User%20-%20180%20days

Tuesday, February 20, 2018

Effect of Low-Fat vs Low-Carbohydrate Diet on 12-Month Weight Loss in Overweight Adults and the Association With Genotype Pattern or Insulin Secretion

https://jamanetwork.com/journals/jama/article-abstract/2673150?utm_source=silverchair&utm_medium=email&utm_campaign=article_alert-jama&utm_content=etoc&utm_term=022018&redirect=true

Common Birth Control Shot Linked to Risk of HIV Infection

https://endocrinenews.endocrine.org/common-birth-control-shot-linked-risk-hiv-infection/

Flu Vax Data 'Only Tell Half the Story'

Flu vaccine efficacy numbers may seem lower than normal, but any flu vaccine is better than no vaccine, says William Schaffner, MD, professor of preventive medicine and infectious diseases at Vanderbilt University, in this MedPage Today video. Schaffner characterizes the current vaccine's efficacy numbers as "not bad," and reiterates that vaccination helps prevent severe flu even if it isn't perfect. He also emphasizes the importance of pediatric immunizations, given the latest CDC data about pediatric deaths, and looks ahead to upcoming flu vaccine research. Following is a transcript of his remarks: https://www.medpagetoday.com/infectiousdisease/uritheflu/71237?xid=nl_mpt_DHE_2018-02-20&eun=g721819d0r&pos=1&utm_source=Sailthru&utm_medium=email&utm_campaign=Daily%20Headlines%202018-02-20&utm_term=Daily%20Headlines%20-%20Active%20User%20-%20180%20days

Ketone Supplement Drink May Reduce Glycemic Response, Improve Markers Of Insulin Sensitivity,

A ketone supplement, taken as a so-called ‘keto drink’ half an hour prior to consuming glucose, reduces glycemic response and improves markers of insulin sensitivity without affecting insulin secretion,” researchers reported. http://onlinelibrary.wiley.com/doi/10.1113/JP275709/full

Saturday, February 17, 2018

Asthma Treatment May Impact Time To Conception

reports that “in an analysis of data from the international Screening for Pregnancy Endpoints (SCOPE) study, no significant difference in time to conception was seen among non-asthmatic women and asthmatic women taking inhaled corticosteroids with and without long-acting β-agonists.” However, “women with asthma using short-acting beta agonist drugs alone took, on average, about 20% longer to conceive and were 30% more likely to take more than a year to get pregnant compared with women without asthma.” https://www.forbes.com/forbes/welcome/?toURL=https://www.forbes.com/sites/helenthomson/2018/02/14/asthma-linked-to-infertility-in-women-who-only-take-short-term-medication/&refURL=&referrer=

Shorter Steroid Courses Hold Promise in Autoimmune Vasculitis

https://www.medpagetoday.com/rheumatology/generalrheumatology/71179?xid=nl_mpt_DHE_2018-02-16&eun=g721819d0r&pos=2&utm_source=Sailthru&utm_medium=email&utm_campaign=Daily%20Headlines%202018-02-16&utm_term=Daily%20Headlines%20-%20Active%20User%20-%20180%20days

Flu Vax Efficacy 25% Against Predominant H3N2 Strain So Far Vaccine still effective at preventing deaths, experts say

https://www.medpagetoday.com/infectiousdisease/uritheflu/71181?xid=nl_mpt_DHE_2018-02-16&eun=g721819d0r&pos=0&utm_source=Sailthru&utm_medium=email&utm_campaign=Daily%20Headlines%202018-02-16&utm_term=Daily%20Headlines%20-%20Active%20User%20-%20180%20days

Thursday, February 15, 2018

Premature Death Risk Seen in Single Dads Higher rates than both single moms and partnered fathers

https://www.medpagetoday.com/primarycare/generalprimarycare/71171?xid=NL_breakingnews_2018-02-15&eun=g721819d0r&utm_source=Sailthru&utm_medium=email&utm_campaign=MorningBreak_021518&utm_term=Morning%20Break%20-%20Active%20Users%20-%20180%20days

Ultra-Processed Foods May Be Associated With Higher Risk Of Cancer

reports that the study “is the first to explore the link between cancer and ultra-processed foods...says [one] study author.” Results indicate, however, that not all processed foods may be equal, since “drinks, sugary products, fats and sauces were most strongly associated with a heightened cancer risk... [and] sugary processed foods were most strongly linked to breast cancer.” http://time.com/5157885/processed-foods-cancer/

Reducing Calorie Consumption May Be Likely To Spark Changes That Permanently Boost Appetite Among Obese Men And Women,

https://consumer.healthday.com/vitamins-and-nutrition-information-27/obesity-health-news-505/it-s-not-your-imagination-you-re-hungrier-after-losing-weight-731144.html “Cutting back on calorie consumption is likely to spark changes that permanently boost appetite among obese men and women,” research indicated. The findings were published online in the American Journal of Physiology-Endocrinology and Metabolism.

Daily Six-Ounce Serving Of 100% Fruit Juice May Lead To Weight Gain In Post-Menopausal Women Over Three Years

reports that post-menopausal women “who drink a small glass of fruit juice daily can expect to steadily gain a bit of weight over the years,” researchers found after analyzing data from the Women’s Health Initiative. In fact, “a single 6-ounce daily serving of 100-percent fruit juice every day prompted an average weight gain of about half a pound over three years,” the study revealed. The findings were published online in Preventive Medicine. https://consumer.healthday.com/vitamins-and-nutrition-information-27/food-and-nutrition-news-316/one-hidden-culprit-behind-weight-gain-fruit-juice-731105.html

Wednesday, February 14, 2018

Numerous Factors Contributing To Precipitous Decline In America’s Fertility, Economist Explains.

“The Upshot,” economist Lyman Stone at Demographic Intelligence writes, “America’s fertility is in precipitous decline,” as projected by a “team of forecasters at Demographic Intelligence.” The forecasters projected “3.84 million births in 2017, down from about 3.95 million in 2016.” Stone breaks down the data in detail, concluding that “with marriage coming later, the share of women at peak childbearing ages (20 to 40) who are married has steadily fallen.” At the same time, “unmarried births are falling, too.” Americans appear to be “having less sex than they used to,” and people in the US “are improving their ability to avoid unwanted pregnancies far faster than they are improving the ability to achieve desired pregnancy.” https://www.nytimes.com/2018/02/13/upshot/american-fertility-is-falling-short-of-what-women-want.html

Nonstick Chemicals May Disrupt Metabolic Function in Women Higher PFAS concentrations tied to weight regain, slower metabolism

https://www.medpagetoday.com/publichealthpolicy/environmentalhealth/71128?xid=nl_mpt_DHE_2018-02-14&eun=g721819d0r&pos=2&utm_source=Sailthru&utm_medium=email&utm_campaign=Daily%20Headlines%202018-02-14&utm_term=Daily%20Headlines%20-%20Active%20User%20-%20180%20days

Tuesday, February 13, 2018

Worst Flu Season Yet? Three years ago was worse, CDC says

https://www.medpagetoday.com/infectiousdisease/uritheflu/71094?xid=nl_mpt_DHE_2018-02-13&eun=g721819d0r&pos=1&utm_source=Sailthru&utm_medium=email&utm_campaign=Daily%20Headlines%202018-02-13&utm_term=Daily%20Headlines%20-%20Active%20User%20-%20180%20days But just this morning on CNN, they said this flu season is the worst since 2009 outbreak as far as the number of deaths.

Prescription Opioid Use Tied to Higher Pneumonia Risk Opioid use represents novel risk factor for invasive pneumococcal diseases

Prescription opioid use was strongly associated with an increased risk for laboratory-confirmed pneumonia, meningitis, and other invasive pneumococcal diseases (IPD), with the most robust associations seen in users of long-acting, high-potency opioid pain relievers, researchers reported. https://www.medpagetoday.com/psychiatry/opioids/71112?xid=nl_mpt_DHE_2018-02-13&eun=g721819d0r&pos=0&utm_source=Sailthru&utm_medium=email&utm_campaign=Daily%20Headlines%202018-02-13&utm_term=Daily%20Headlines%20-%20Active%20User%20-%20180%20days

Patients With Diabetes May Be At Greater Risk Of Developing Cataracts

reports researchers found “patients with diabetes have a twofold increased risk of developing cataracts compared with the general population,” and “the risk is even higher among younger diabetes patients.” The findings were published in the journal Eye. https://www.nature.com/articles/s41433-017-0003-1.epdf?referrer_access_token=85w4NzKRSIjHBFS6HpL4-NRgN0jAjWel9jnR3ZoTv0Nmg_3u3aNad8wT9kxw5fWiLvGSEhC1JMSiaEVBKazV7Emk1ClJ6OuZAUsTsTJyuf_IbT5O0tWyRwlqNd6PioLeiNp3EZ8RW2X7BHJM-E2pT6V7dXs1pgRyhZwYEsfmZGvIPqsIFpU4atdXd0BSER0j&tracking_referrer=www.medscape.com

Obesity-Related Healthcare Spending Up 29 Percent Since 2001, Study Suggests.

reports a study from Cornell University found that US medical expenditures “focused on obesity-related procedures and therapies for adults” increased 29 percent from 2001 to 2015, although the percentages varied by state. The study’s co-author, John Cawley, said, “We have, for the first time, estimated the percentage of health care spending that is devoted to obesity, using microdata for each state.” For instance, over 20 percent of Medicaid spending in Kentucky and Wisconsin is for obesity-related illnesses, compared to 10.9 percent in New York. http://www.nydailynews.com/life-style/u-s-healthcare-costs-29-obesity-article-1.3816398

How Viruses Disarm the Immune System

https://www.technologynetworks.com/tn/news/how-viruses-disarm-the-immune-system-297329?utm_campaign=NEWSLETTER_TN_Immunology_2017&utm_source=hs_email&utm_medium=email&utm_content=60639987&_hsenc=p2ANqtz-8EjZH-4f9NrmLiYo8hXNu_btxljxRHiZ_fz8fZEOENda_OOMhxhyJFB287Sw2V8x4asNqIKSXtDh7EaS2T6S7v2zdglg&_hsmi=60639987

E-cigarette Flavors Toxic to White Blood Cells

https://www.technologynetworks.com/tn/news/e-cigarette-flavors-toxic-to-white-blood-cells?utm_campaign=NEWSLETTER_TN_Immunology_2017&utm_source=hs_email&utm_medium=email&utm_content=60639987&_hsenc=p2ANqtz-8EjZH-4f9NrmLiYo8hXNu_btxljxRHiZ_fz8fZEOENda_OOMhxhyJFB287Sw2V8x4asNqIKSXtDh7EaS2T6S7v2zdglg&_hsmi=60639987

People Often Overdo it with NSAIDS Report shows 15% of users exceed the recommended dose

https://www.medpagetoday.com/rheumatology/generalrheumatology/71063?xid=nl_mpt_DHE_2018-02-12&eun=g721819d0r&pos=2&utm_source=Sailthru&utm_medium=email&utm_campaign=Daily%20Headlines%202018-02-12&utm_term=Daily%20Headlines%20-%20Active%20User%20-%20180%20days

Friday, February 9, 2018

Cheese triggers the same part of the brain as hard drugs, say scientists

https://www.standard.co.uk/lifestyle/foodanddrink/cheese-triggers-the-same-part-of-the-brain-as-hard-drugs-say-scientists-a3141936.html

Medicaid Skimps on Hepatitis C Treatment in Many States Report finds restrictions based on liver disease severity, sobriety, and type of provider

https://www.medpagetoday.com/reading-room/aga/lower-gi/71030?xid=nl_mpt_DHE_2018-02-09&eun=g721819d0r&pos=0&utm_source=Sailthru&utm_medium=email&utm_campaign=Daily%20Headlines%202018-02-09&utm_term=Daily%20Headlines%20-%20Active%20User%20-%20180%20days

Scientists Say They Have Grown Human Eggs To Full Maturity In A Lab.

reports that scientists have, for the first time, grown human eggs in a laboratory from the “earliest stages in ovarian tissue all the way to full maturity.” The scientists from two research hospitals in Edinburgh and the Center for Human Reproduction in New York published their results in the journal Molecular Human Reproduction Friday. Professor Evelyn Telfer, one of the leaders of the study, said, “Being able to fully develop human eggs in the lab could widen the scope of available fertility treatments.” Independent experts praised the work as “an impressive technical achievement.” https://www.reuters.com/article/us-health-human-eggs/scientists-grow-human-eggs-to-full-maturity-in-a-lab-idUSKBN1FT00P

Thursday, February 8, 2018

Gene Assay Informs Chemo Decision in Breast Cancer 10-year recurrence risk of 3.5% in low-risk, node-positive disease

This study identified a substantial population of patients with one to three positive lymph nodes with sufficiently low risk to safely avoid chemotherapy. By tailoring risk categorization to the number of positive nodes, 37% of patients with a single positive lymph node and 15% of patients with two positive nodes were characterized as low risk, by Prosigna, with very favorable outcomes when treated with adjuvant endocrine therapy alone. "Although chemotherapy could still provide some relative additional benefit for patients, when the low-risk group carries a residual rate of recurrence of <5% at 10 years, the absolute benefit that can be achieved by still giving chemotherapy could be, at best, very small (and more than counterbalanced by toxicities)."

Metabolic Surgery May Be Superior To Medical Treatment For Prevention Of Microvascular Complications In T2D

“Metabolic surgery was superior to medical treatment for the prevention of microvascular complications in type 2 diabetes [T2D],” research indicated. The findings of the multi-study meta-analysis were published in the British Journal of Surgery.

YIKES Some Diabetes Patients May Be Injecting Insulin That Has Partially Disintegrated, Research Indicates.

reports that “preliminary research” on just “18 vials of insulin” suggests that “some diabetes patients may be injecting medicine that has partially disintegrated.” The study’s author, a pharmacist, purchased “vials of insulin at a number of pharmacies and found that on average the vials had less than half of what was listed on the label and none met a minimum standard.” The findings were published online in the Journal of Diabetes Science and Technology. https://apnews.com/ccfc2712fa3e469fad2179beede78827/Insulin-quality-questions-have-diabetes-experts-scrambling

Wednesday, February 7, 2018

Fat Lost On Crash Diets May Have Negative Impact On Heart Health

reports that a study “suggests that fat lost on crash diets may clog the heart and reduce its function.” However, “this effect appears temporary.” Rayner's team theorized that the sudden drop in calories causes fat to be released from different parts of the body into the blood. It's then taken up by the heart muscle. But the negative changes didn't last. By eight weeks, heart function and heart fat were better than normal. Body fat, cholesterol and all of the other metabolic measures also continued to improve. The findings were presented at the European Society of Cardiology meeting. https://consumer.healthday.com/vitamins-and-nutrition-information-27/dieting-to-lose-weight-health-news-195/crash-diets-might-derail-your-heart-health-730863.html

Lung Disease Common in Late-Onset SLE Rates of interstitial lung disease more than doubled

Many potential factors may contribute to the increased pulmonary risks among late-onset lupus patients, including effects on both the innate and adaptive immune systems. For example, neutrophils in older individuals are less capable of killing phagocytosed pathogens but have increased apoptosis, and thymic production of naive T-cells declines, leading to proliferation of memory T cells and a resulting proinflammatory state. An additional contributory factor for interstitial lung disease in older patients may be a possible SLE-Sjogren's syndrome overlap syndrome, which has been reported by several groups. The prevalence of interstitial lung disease in Sjogren's syndrome, at 9% to 75%, is much higher than in SLE, at 1% to 15%, so an overlap syndrome could explain the high incidence in older patients. "In addition to a possible Sjogren's overlap phenotype in late-onset SLE, factors such as duration of disease, environmental exposures, and smoking trends over time might also correlate with SLE interstitial lung disease," the researchers observed. https://www.medpagetoday.com/rheumatology/lupus/70981?xid=nl_mpt_DHE_2018-02-07&eun=g721819d0r&pos=0&utm_source=Sailthru&utm_medium=email&utm_campaign=Daily%20Headlines%202018-02-07&utm_term=Daily%20Headlines%20-%20Active%20User%20-%20180%20days

Tuesday, February 6, 2018

ACIP Issues Updated Adult Vax Schedule Changes to shingles, MMR vaccine recommendations

Changes to the adult immunization schedule include a preferential recommendation for a new recombinant zoster vaccine for older adults, and a third dose of measles mumps rubella (MMR) vaccine to adults who may be at risk of mumps during an outbreak. The CDC Advisory Committee for Immunization Practices (ACIP) recommended changes on use of herpes zoster vaccine and use of an additional MMR dose, with additional changes in the wording of tetanus, diphtheria, and pertussis (Tdap), and other vaccine recommendations, wrote David K. Kim, MD, on behalf of the ACIP, and colleagues, in the Annals of Internal Medicine. The authors noted that the ACIP updated the standards of adult immunization practice "to promote the integration of vaccinations as a part of routine clinical care for adults." This means healthcare providers should assess a patient's vaccination status at every clinical encounter, "strongly recommend" needed vaccines to patients, offer vaccines recommended to patients, and document vaccines administered in the state or local immunization information system. https://www.medpagetoday.com/primarycare/vaccines/70970?xid=nl_mpt_DHE_2018-02-06&eun=g721819d0r&pos=3&utm_source=Sailthru&utm_medium=email&utm_campaign=Daily%20Headlines%202018-02-06&utm_term=Daily%20Headlines%20-%20Active%20User%20-%20180%20days

CSF Inflammatory Cytokines Linked to Perinatal Depression Novel research supports neuroinflammatory mechanism

They hypothesized that similar to depression outside of pregnancy, perinatal depression may be associated with CSF cytokines. https://www.medpagetoday.com/meetingcoverage/smfm/70953?xid=nl_mpt_DHE_2018-02-06&eun=g721819d0r&pos=1&utm_source=Sailthru&utm_medium=email&utm_campaign=Daily%20Headlines%202018-02-06&utm_term=Daily%20Headlines%20-%20Active%20User%20-%20180%20days

Researchers To Study Mixed Metals Mining Contamination On Native American Populations.

reports that the newly-established Superfund Research Center at the University of New Mexico hopes to “measure the effects of mixed metals and uranium waste exposure on Native American populations living in close proximity to abandoned mines, and better understand how these toxins spread through the environment.” The piece notes that there are 4,000 abandoned uranium mines and 160,000 abandoned hard rock mines throughout the West with 600,000 Native Americans living within six miles of those sites. The research is funded by a five-year, $1.2 million per year grant from the National Institute of Environmental Health Sciences. https://www.abqjournal.com/1129580/researchers-to-measure-mixed-metals-mining-contamination-on-native-americans.html

Monday, February 5, 2018

More Teens Identify As Transgender Or Gender Nonconforming Than Previously Believed, Study Suggests.

reports a new study published in Pediatrics analyzed almost 81,000 students in ninth and 11th grade and found that nearly 2,200, or nearly three percent, identified as transgender or gender nonconforming. The study found that these children reported worse mental and physical health than other kids, echoing results seen in previous research. The AP adds that an “American Academy of Pediatrics policy...says pediatricians should use gender-neutral terms and encourage teens to feel comfortable talking ‘about their emerging sexual identities.’” https://www.washingtonpost.com/national/health-science/not-just-boy-and-girl-more-teens-identify-as-transgender/2018/02/04/0c2df5da-09f8-11e8-998c-96deb18cca19_story.html?utm_term=.65e6307713dc

Plastic Chemical Linked To Male Infertility Found In Most Teenagers.

reports that 86 percent of teenagers have traces of Bisphenol A, a plastics chemical linked to reduced fertility in men, according to a new study. The study involved 94 students at Devon schools who were instructed to limit their exposure to plastics for a week. Overall, they did not see a drop in their recorded levels. http://www.telegraph.co.uk/news/2018/02/04/plastic-chemical-linked-male-infertility-majority-teenagers/

Sleep for Weight Loss Can sleeping more make patients healthier?

https://www.medpagetoday.com/primarycare/dietnutrition/70951?xid=NL_breakingnews_2018-02-05&eun=g721819d0r&utm_source=Sailthru&utm_medium=email&utm_campaign=MorningBreak_020518&utm_term=Morning%20Break%20-%20Active%20Users%20-%20180%20days

Friday, February 2, 2018

Exposure Of Explants Of Human Fetal Ovaries To Ibuprofen For Short Periods May Be Associated With A Sharp Decrease In Germ Cells,

“Exposure of explants of human fetal ovaries to ibuprofen for short periods is associated with a sharp decrease in the number of germ cells,” researchers found. The study authors wrote, “The findings raise ‘concern about ibuprofen consumption by pregnant women during the fetal ovarian organogenesis period and a subsequent risk for the establishment of the follicular reserve.’” The findings were published online in Human Reproduction. https://academic.oup.com/humrep/advance-article/doi/10.1093/humrep/dex383/4831088

Thursday, February 1, 2018

Vitamin D3 Supplements May Be Beneficial For Patients With Or At Risk For Heart Disease,

contributor David DiSalvo writes that research published in the International Journal of Nanomedicine suggests vitamin D3 supplements may be beneficial for individuals “at risk for or already have heart disease.” Cardiovascular Business (1/31, Slachta) reports that investigators “found vitamin D3 to be a powerful stimulator of nitric oxide, which is key in regulating blood flow and preventing the formation of clots.” Additionally, “the vitamin...appeared to significantly reduce the level of oxidative stress in the cardiovascular system.” http://www.cardiovascularbusiness.com/topics/acute-coronary-syndrome/high-doses-vitamin-d-shown-restore-cardiovascular-system-post-heart-attack

Average American Could Lose Nearly Six Pounds Of Fat Per Year By Standing Six Hours Each Day

reports a new study published in the European Journal of Preventive Cardiology suggests that if Americans, who sit an average of more than seven hours each day, were to stand for six of those hours, the average person “would burn an additional 54 calories a day.” This, researchers found, “could translate into a loss of about 5.5 pounds of body fat per year” for the average American, excluding diet changes and extraneous exercise. http://www.latimes.com/science/sciencenow/la-sci-sn-standing-burns-calories-20180131-story.html