Acne Improves Without Use of Antibiotics

One-third of patients with moderate or severe acne in a large randomized trial had significant improvement in acne severity and lesion count with an antibiotic-free topical gel versus placebo, results showed. After 12 weeks of treatment, 33.7% of patients treated with 0.3% adapalene/benzoyl peroxide (A/BPO) had at least a two-grade improvement in acne severity grade as compared with 11% of patients treated with a placebo gel. A subgroup analysis limited to patients with severe acne showed success rates of 31.9% with 0.3% A/BPO and 11.8% with the placebo.http://www.medpagetoday.com/MeetingCoverage/AAD/50621?xid=nl_mpt_DHE_2015-03-24eun=g721819d0r&userid=721819&email=amydugan2@gmail.com&mu_id=5883165