Genetic Predisposition To Higher Abdominal Adiposity May Be Linked To Higher Risk For Cardiometabolic Traits And Type 2 Diabetes, Study Suggests.

reports that in the “Mendelian randomization analysis, having a polygenetic predisposition for abdominal fat was tied to having increased levels of cardiometabolic risk factors and a greater risk of developing type 2 diabetes and CHD.” In particular, “each one-standard-deviation increase in waist-to-hip ratio based on the polygenic risk score and adjusted for BMI was associated with 27-mg/dL higher triglyceride levels, 4.1-mg/dL higher 2-hour glucose levels, and 2.1–mm Hg higher systolic blood-pressure levels. http://www.medpagetoday.com/endocrinology/diabetes/63116 The authors plan to continue their research, in the hopes of identifying "individual genes, which could be targeted to improve body fat distribution and potentially reduce the risk of type 2 diabetes and coronary heart disease," Emdin told MedPage Today. So I can blame my genes and prednisone for fat belly despite swimming half mile every day and eating right.