Mouse Study Finds Prenatal BPA Exposure May Change Brain’s Processing Of Satiety Signals.

reports a mouse study in Endocrinology found that prenatal exposure to BPA “alters the way the brain deals [with] signals of ‘hungry’ or ‘full’ later in life.” Mice exposed to BPA failed to develop “satiety circuitry” in the brain so that as adults they failed to respond to the presence of leptin, “the metabolic signal telling the brain how much fat is in the body.” Thomas Zoeller, an endocrinologist at the University of Massachusetts in Amherst, said that similarly, “Children that have genetic defects in their leptin signaling system are absolutely obese.” Thaddeus Schug, of the National Institute of Environmental Health Sciences, pointed out that the BPA doses in the study are “some 10-100 times higher than what we humans are normally exposed to.” Schug said that it is important for there to be more communication among the FDA, EPA, industry and the NIH. http://www.popsci.com/our-mothers-exposure-to-bpa-might-lead-us-to-over-eat-as-adults