Diagnosing Early Lupus from Mimics Certain clinical features may distinguish early SLE from other conditions

They found that features that were more common in early SLE than in SLE‐mimicking conditions included: Unexplained fever 34.5% versus 13.7%, respectively (P<0.001) Anti-double-stranded DNA, anti-β2-glycoprotein I antibodies, positive Coombs' test results, autoimmune hemolytic anemia, hypocomplementemia, and leukopenia Features that were less common in early SLE than in SLE‐mimicking conditions included: Raynaud's phenomenon (22.1% versus 48.5%, P<0.001) Sicca symptoms (4.4% versus 34.4%, P<0.001) Dysphagia (0.3% versus 6.2%, P<0.001) Fatigue (28.3% versus 37.0%, P=0.024) https://www.medpagetoday.com/rheumatology/lupus/76793?xid=nl_mpt_DHE_2018-12-10&eun=g721819d0r&pos=1&utm_source=Sailthru&utm_medium=email&utm_campaign=Daily%20Headlines%202018-12-10&utm_term=NL_Daily_DHE_Active