Gut Bugs Differ in Chronic Prostatitis

The gut microbiome was altered in men with chronic prostatitis/chronic pelvic pain syndrome (CPPS) versus controls, researchers reported here. Microbiome processing of fecal matter using next-generation RNA gene sequencing and bioinformatics analyses revealed underrepresentation of several taxa, including Prevotella, in the guts of men with chronic prostatitis/CPPS compared with controls, according to Daniel Shoskes, MD, from the Cleveland Clinic, and colleagues. Prevotella is a genus of gram-negative bacteria that protects against inflammation. Data from gut microbiome analyses may eventually allow for identification of potential biomarkers and targets of therapy, he reported in a presentation at the American Urological Association meeting. In humans, the number of bacterial genes exceeds the number of human genes by a factor of at least 100:1. http://www.medpagetoday.com/MeetingCoverage/AUA/57833?xid=NL_breakingnews_2016-05-11&eun=g721819d0r