Study Ties Common Heartburn Medications to Kidney Disease

YIKES Use of proton pump inhibitors (PPI), a group of drugs that reduce the production of stomach acid, increases the risk of chronic kidney disease by 20 percent and raises the risk of kidney failure by four times. Risks were highest among people at least 65 years old. The research, published in February in Pharmacotherapy, is one of the first large, long-term studies to examine the effects of PPIs on kidney function. Researchers examined the health data of more than 190,000 patients over a 15-year period. "This study adds to a growing list of concerning side effects and adverse outcomes associated with PPIs," says David Jacobs, PharmD, PhD, lead investigator and assistant professor of pharmacy practice in the UB School of Pharmacy and Pharmaceutical Sciences. "Given the increasing global use of PPIs, the relationship between PPIs and renal disease could pose a substantial disease and financial burden to the health care system and public heal. https://www.technologynetworks.com/drug-discovery/news/study-ties-common-heartburn-medications-to-kidney-disease-316881?utm_campaign=NEWSLETTER_TN_Breaking%20Science%20News&utm_source=hs_email&utm_medium=email&utm_content=70907732&_hsenc=p2ANqtz-8NvfANyjjI20a-_ZQ2yrws2asQ2Je-3sSU4DU0O-urNJX_gAm2QR2rtKH1CW097m7_t2FnVpHYe65aEOtVITZtWPbNmw&_hsmi=70907732