Bacteria Invade Deep Into Bladder Wall in UTIs

The investigation demonstrates that several species of bacteria can work their way inside the human bladder’s surface area, called the urothelium, in RUTI patients. Bacterial diversity, antibiotic resistance, and the adaptive immune response all play important roles in this disease, the study suggests. “Our findings represent a step in understanding RUTIs in postmenopausal women,” said Dr. Orth, also an Investigator of the prestigious Howard Hughes Medical Institute who holds the Earl A. Forsythe Chair in Biomedical Science and is a W.W. Caruth, Jr. Scholar in Biomedical Research at UTSW. “We will need to use methods other than antibiotics to treat this disease, as now we observe diverse types of bacteria in the bladder wall of these patients.” Since the advent of antibiotics in the 1950s, patients and physicians have relied on antibiotics for UTI treatment. https://www.technologynetworks.com/diagnostics/news/bacteria-invade-deep-into-bladder-wall-in-utis-319282?utm_campaign=NEWSLETTER_TN_Breaking%20Science%20News&utm_source=hs_email&utm_medium=email&utm_content=72600921&_hsenc=p2ANqtz-8ngtfqEL7SnsKKchYXawRGLMRFpjPmkLZ1Gsq6js-wu1tDeEH3x_xh_cX0vKMeI-_YNU3dd8an3y-mGEPvS2mzlmjicg&_hsmi=72600921