Dr. House

Dr. House
Dr. House

Monday, September 30, 2019

Experts Discuss Trends In Cannabis Use In Menopause

reports at a meeting of the North American Menopause Society, experts discussed cannabis use in menopause, despite a lack of research on the subject. Experts “discussed how rapidly knowledge in the cannabis space is moving, and how patients might weigh scientific knowledge versus lived experience.” Moreover, a presenter reviewed “Google search data that found that ‘CBD for menopause’ was the breakout search, or most rising term, of the last 5 years in searches for menopause.” https://www.medpagetoday.com/meetingcoverage/nams/82461

250,000 Nights of Sleep Measured in Global Study

The findings indicate that there are differences in the duration and timing of sleep by age, geographical region and gender. The timing of sleep was delayed among 16-24-year-old subjects, but in older subjects sleep was again timed earlier. "It was interesting to find that the circadian rhythm shifts later even in people over 20 years of age. It was already previously known that sleep timing is delayed in adolescence. What was clearly highlighted in this study is how long into adulthood this actually carries on," says Liisa Kuula, a postdoctoral researcher at the University of Helsinki. People in Europe and North America slept the longest, while the shortest sleep was observed in Asian countries. Sleep was timed the latest in the Middle East, while the earliest sleep rhythm was found in Oceania. Young women slept more than young men, and the former also went to sleep earlier. "Geographical differences were relatively small but similar to those seen in prior, smaller-scale studies. The need for sleep does not vary greatly between cultures, but differences arise in terms of the time reserved for sleeping," Kuula notes. https://www.technologynetworks.com/neuroscience/news/250000-nights-of-sleep-measured-in-global-study-324488?utm_campaign=NEWSLETTER_TN_Breaking%20Science%20News&utm_source=hs_email&utm_medium=email&utm_content=77446213&_hsenc=p2ANqtz-9IByAjG8aCK18oZNaaXqL4pyzEEMRHSrXCUYSfqnVEpJBUds78GQvs45fXVnT1KLJ6KGLPseIfl81cL3SWTKYcE8ypGQ&_hsmi=77446213

Weight Gain Could Be Linked To Gut Bacteria

https://www.technologynetworks.com/tn/news/weight-gain-could-be-linked-to-gut-bacteria-324480?utm_campaign=NEWSLETTER_TN_Breaking%20Science%20News&utm_source=hs_email&utm_medium=email&utm_content=77446213&_hsenc=p2ANqtz-9IByAjG8aCK18oZNaaXqL4pyzEEMRHSrXCUYSfqnVEpJBUds78GQvs45fXVnT1KLJ6KGLPseIfl81cL3SWTKYcE8ypGQ&_hsmi=77446213

New Blood Test Capable of Detecting Multiple Types of Cancer

https://www.technologynetworks.com/cell-science/news/new-blood-test-capable-of-detecting-multiple-types-of-cancer-324459?utm_campaign=NEWSLETTER_TN_Breaking%20Science%20News&utm_source=hs_email&utm_medium=email&utm_content=77446213&_hsenc=p2ANqtz-9IByAjG8aCK18oZNaaXqL4pyzEEMRHSrXCUYSfqnVEpJBUds78GQvs45fXVnT1KLJ6KGLPseIfl81cL3SWTKYcE8ypGQ&_hsmi=77446213

Friday, September 27, 2019

Baby Teeth May Identify ADHD — How a child metabolizes nutrients and toxins may play a role in ADHD and autism

https://www.medpagetoday.com/neurology/adhd-add/82397?xid=nl_mpt_morningbreak2019-09-27&eun=g721819d0r&utm_source=Sailthru&utm_medium=email&utm_campaign=MorningBreak_092719&utm_term=NL_Daily_Morn_Break_Active

Elevated Serum Levels Of Circulating Sex Hormones Were Found To Be Associated With Lower Odds Of Asthma In Women, Research Suggests

, “Elevated serum levels of circulating sex hormones were found to be associated with lower odds of asthma in women, possibly explaining in part the different prevalence of asthma in men and women,” researchers concluded after analyzing “data from 7,615 adults (3,953 men and 3,662 women) who participated in the 2013-2014 and 2015-2016 U.S. National Health and Nutrition Examination Survey.” The findings were published online in the American Journal of Respiratory and Critical Care Medicine. https://www.mdedge.com/endocrinology/article/208889/asthma/serum-testosterone-and-estradiol-levels-associated-current

Middle-Aged And Older Adults Who Live In Greener Neighborhoods May Have Decreased Risk Of Developing Metabolic Syndrome, Research Indicates

reports research indicates that “middle-aged and older adults who live in greener neighborhoods have a decreased risk of developing metabolic syndrome.” Included in the study were some 6,000 “British adults.” The findings were published online in the journal Environmental Pollution. https://www.newsweek.com/study-finds-people-living-near-green-spaces-less-prone-factors-associated-obesity-heart-disease-1461623

Tuesday, September 24, 2019

Largest Study to Date Shows Promise for Vitamin D and Fish Oil in Cancer Prevention

The VITamin D and OmegA-3 Trial (VITAL) is the largest and most recent to test whether vitamin D or fish oil can effectively prevent cancer or cardiovascular disease. Results to date have been mixed but show promise for some outcomes, now confirmed by updated pooled (meta) analyses. The latest results from VITAL will be presented during The North American Menopause Society (NAMS) Annual Meeting in Chicago, September 25-28, 2019. Nearly 26,000 U.S. men and women participated in the nationwide VITAL clinical trial. After more than five years of study and treatment, the results show promising signals for certain outcomes. For example, while Omega-3 fatty acids (fish oil) showed only a small, but nonsignificant, reduction in the primary cardiovascular endpoint of major CVD events, they were associated with significant reductions in heart attacks. https://www.technologynetworks.com/proteomics/news/largest-study-to-date-shows-promise-for-vitamin-d-and-fish-oil-in-cancer-prevention-324243?utm_campaign=NEWSLETTER_TN_Breaking%20Science%20News&utm_source=hs_email&utm_medium=email&utm_content=77210394&_hsenc=p2ANqtz--Hi65Xuh7TU5ZqGTirK23DgbxR3zIGhGRwFTqw0b6tS5cagXCcYPCDzmrxzKC7Lz1q5lqcR56_oeV7rt01Tq45t4gHfQ&_hsmi=77210394

"Breakthrough" Brain Implant Restores Visual Perception

Seven years ago, Jason Esterhuizen was in a horrific car crash that destroyed his eyes, plunging him into total darkness. Today, he’s regained visual perception and more independence, thanks to an experimental device implanted in his brain by researchers at UCLA Health. “Now I can do things that I couldn’t do before,” said Esterhuizen, 30, who moved from his native South Africa to participate in the clinical trial at UCLA. “I can sort the laundry, find my way in lighted hallways without using a cane and cross the street more safely. It’s making my life much easier.” The device is geared to people who used to be able to see but lost their vision to injury or disease. While it doesn’t provide normal sight, it enhances users’ ability to navigate the world by restoring their capacity to detect movement and distinguish light and dark. “This is the first time we've had a completely implantable device that people can use in their own homes without having to be plugged into an external device,” said Dr.Nader Pouratian, a neurosurgeon at UCLA Health and principal investigator of the five-year study. “It helps them recognize, for example, where a doorway is, where the sidewalk begins or ends or where the crosswalk is. These are all extremely meaningful events that can help improve people’s quality of life.” https://www.technologynetworks.com/neuroscience/news/breakthrough-brain-implant-restores-visual-perception-324251?utm_campaign=NEWSLETTER_TN_Breaking%20Science%20News&utm_source=hs_email&utm_medium=email&utm_content=77210394&_hsenc=p2ANqtz--Hi65Xuh7TU5ZqGTirK23DgbxR3zIGhGRwFTqw0b6tS5cagXCcYPCDzmrxzKC7Lz1q5lqcR56_oeV7rt01Tq45t4gHfQ&_hsmi=77210394

Wednesday, September 18, 2019

Don’t Make Important Decisions on an Empty Stomach

Participants in an experiment designed by Dr Vincent were asked questions relating to food, money and other rewards when satiated and again when they had skipped a meal. While it was perhaps unsurprising that hungry people were more likely to settle for smaller food incentives that arrived sooner, the researchers found that being hungry actually changes preferences for rewards entirely unrelated to food. This indicates that a reluctance to defer gratification may carry over into other kinds of decisions, such as financial and interpersonal ones. Dr Vincent believes it is important that people know that hunger might affect their preferences in ways they don’t necessarily predict. There is also a danger that people experiencing hunger due to poverty may make decisions that entrench their situation. “We found there was a large effect, people’s preferences shifted dramatically from the long to short term when hungry,” he said. “This is an aspect of hu https://www.technologynetworks.com/applied-sciences/news/dont-make-important-decisions-on-an-empty-stomach-324068?utm_campaign=NEWSLETTER_TN_Breaking%20Science%20News&utm_source=hs_email&utm_medium=email&utm_content=76980822&_hsenc=p2ANqtz-_dIX3l9oYtCUpR8FiOkifmFNX5YuZ7Q3-mXACgNMhqR2jH9R0PWVcnDAJu2cTRilv1eRLNPE2G8pSkOgDwF6FOJHA7-g&_hsmi=76980822

Research Suggests Air Pollution Can Travel To The Placenta During Pregnancy

reports using a novel scanning technique, researchers “spotted a type of particle pollution — sootlike black carbon — on placentas donated by 28 new mothers.” The study “suggests when a pregnant woman breathes in air pollution, it can travel beyond her lungs to the placenta.” The findings (9/17, Bové) were published in Nature Communications. Reuters (9/17, Emery) reports the study “found that the more https://www.apnews.com/41bb3181463e4841b1464d5a459f756f

Tuesday, September 17, 2019

Benefits Of Aspirin May Outweigh Harms Of Bleeding In Select Group Of Patients, Researchers Say

reports the authors of a 245,000-adult study have “concluded that the benefits of aspirin outweigh the harms of bleeding, if you compared the risk of death from one bleeding event compared to the risk of hospitalization or death from a cardiac event.” CNN adds that the study authors “don’t make an argument to change the current guidelines, which were created for the United States by the American College of Cardiology and American Heart Association.” https://www.cnn.com/2019/09/16/health/aspirin-heart-health-study/index.html

Teenage Girl “Night Owls” May Have Higher Waist Circumference And Greater Adiposity Than “Morning Lark” Peers, Study Suggests

reports researchers found that teenage girls who are “night owls” have “higher waist circumference and greater abdominal fat deposition (adiposity) than” their peers who are “morning larks.” The findings were published in JAMA Pediatrics. https://consumer.healthday.com/sleep-disorder-information-33/misc-sleep-problems-news-626/later-bedtimes-could-mean-wider-waistlines-for-teen-girls-750255.html

Monday, September 16, 2019

Abnormal Breast Growth In Young Girls Tied To Lavender Oil Exposure, Study Indicates

reported researchers found that “abnormal breast growth in young girls is linked to lavender oil exposure.” The findings were published in the Journal of Clinical Endocrinology & Metabolism. https://endocrinenews.endocrine.org/lavender-oil-may-lead-to-abnormal-breast-growth-in-young-girls/

Friday, September 13, 2019

Diabetes Drug Promotes Brain Repair – But It Only Works in Females

the researchers’ delight, metformin was able to activate neural stem cells in the brain and promote cognitive recovery, as shown by mice who were able to learn new tasks and form short and long-term memories. But the data also revealed something unexpected. Metformin did not affect all the animals in equal manner. It only worked in adult females. “When we first looked at the data, we did not see the benefit of the metformin treatment,” says Morshead. “Then we noticed that adult females tended to do better than the males.” A closer look revealed that metformin selectively activated the adult female neural stem cells while having no effect on the males. This turned out to be due to the female sex hormone estradiol, which somehow enhances the stem cells’ ability to respond to metformin. Conversely, the male hormone testosterone appears to inhibit this process. When female mice had their ovaries removed and lacked the female sex hormone, the stem cells did not respond to metformin treatment. “To know that there are both age and sex dependent effects —it has such implications for treatment and therapeutics,” says Morshead. The findings come at a time when scientists are reckoning with the data bias that is skewed against women due to the predominant use of male animals in research. “The thinking was that we’re going to study males because everything you need to know is found in the male brain, and then the female brain just complicates things with hormones,” says Morshead. “It’s very misguided and troublesome for advancing neurological health.” https://www.technologynetworks.com/drug-discovery/news/diabetes-drug-promotes-brain-repair-but-it-only-works-in-females-323928?utm_campaign=NEWSLETTER_TN_Breaking%20Science%20News&utm_source=hs_email&utm_medium=email&utm_content=76805145&_hsenc=p2ANqtz--u49pdeVBD98UX2uFGcRS_PWLYL2WFBshw067mympDy494dr0LdkDmmQxaT0ngb-khfnrUgB7s8qNMSaC3vXt-ZxUgHg&_hsmi=76805145

Wednesday, September 11, 2019

Eating Unhealthy, High-Carb, High-Fat Diet May Change Part Of Brain Controlling Metabolism, Research In Mice Suggests

reports research in mice indicates that “eating an unhealthy, high-carb and high-fat diet does not only impact physical health,” but “it also changes the part of the brain that controls the metabolism.” Investigators “showed the high fat diet seemed to trigger changes in cell powerhouses – or mitochondria – of microglial cells, causing them to spring into action.” The findings were published in the journal Cell Metabolism. https://www.newsweek.com/eating-unhealthy-high-fat-high-carb-diet-also-very-bad-brain-scientists-say-1458429

Tuesday, September 10, 2019

Shorter People May Be At Greater Risk For Developing T2D, Researchers Say

reports, “Shorter people are at greater risk of developing type 2 diabetes [T2D],” researchers concluded after looking at some “2,500 middle-aged men and women in Germany from a pool of about 26,000 people.” After adjusting for confounding factors, investigators found that “greater height was associated with a lower risk for diabetes.” The findings were published online in the journal Diabetologia. https://www.cnn.com/2019/09/09/health/shorter-people-diabetes-trnd/index.html

Flu Vaccine Effectiveness May Be Impacted by Microbiome Disruption

The normal human gut microbiome is a flourishing community of microorganisms, some of which can affect the human immune system. In a new paper published this week in Cell, researchers found that oral antibiotics, which can kill gut microorganisms, can alter the human immune response to seasonal influenza vaccination. The work was led by scientists at Stanford University and funded by the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health. The research team examined 33 healthy adult participants in their study. One group of 22 volunteers was studied during the 2014-2015 flu season, and the second group with 11 volunteers was studied during the 2015-2016 flu season. The group of 22 volunteers had high pre-existing immunity to the influenza virus strains contained in the 2014-2015 seasonal influenza vaccine. The group of 11 volunteers had low immunity to the 2015-2016 seasonal influenza vaccine’s virus strains. https://www.technologynetworks.com/tn/news/flu-vaccine-effectiveness-may-be-impacted-by-microbiome-disruption-323686?utm_campaign=NEWSLETTER_TN_Breaking%20Science%20News&utm_source=hs_email&utm_medium=email&utm_content=76589541&_hsenc=p2ANqtz--CVxIJ4gZuuqXE2T28bbOjBEr3vlRqpRQEmXOhUbdqhqdxVMC1WBlsACqi-xQiKBX8EaptZBigwrpiJ7K9sAEI3i2ixg&_hsmi=76589541

Compound Created to Help Reconstruct Myelin in Multiple Sclerosis

Researchers have created a compound, that when tested in mice, was able to promote the reconstruction of the myelin sheath surrounding neuronal axons. These findings could pave the way to a new treatment for combating demyelinating conditions such as multiple sclerosis (MS). The findings were published in Glia. "I think we'll know in about a year if this is the exact right drug to try in human clinical trials," explained senior study author Larry Sherman, Ph.D., in a recent press release. "If it's not, we know from the mouse studies that this approach can work. The question is, can this drug be adapted to bigger human brains?" https://www.technologynetworks.com/drug-discovery/news/compound-created-to-help-reconstruct-myelin-in-multiple-sclerosis-323575?utm_campaign=NEWSLETTER_TN_Breaking%20Science%20News&utm_source=hs_email&utm_medium=email&utm_content=76589541&_hsenc=p2ANqtz--CVxIJ4gZuuqXE2T28bbOjBEr3vlRqpRQEmXOhUbdqhqdxVMC1WBlsACqi-xQiKBX8EaptZBigwrpiJ7K9sAEI3i2ixg&_hsmi=76589541

Thursday, September 5, 2019

Testosterone Appears Not To Make It Harder For Men To Empathize, Researchers Say

Testosterone doesn’t make it harder for men to empathize, according to” researchers “who have questioned the idea that the hormone distorts this ability in people with autism.” The findings of the large all-male study were published online Sept. 4 in the journal Proceedings of the Royal Society B. https://www.newsweek.com/extreme-male-brain-theory-autism-overturned-huge-study-finds-no-link-between-testosterone-lack-1457209

Warm weather, walkable neighborhoods tied to lower blood pressure in kids

Kids who grow up in warmer climates and in walkable neighborhoods may have lower blood pressure than those who live where it’s cooler and people drive everywhere, a new European study suggests. Researchers examined data on 1,277 mother-child pairs from the U.K., France, Spain, Lithuania, Norway, and Greece to see how exposures to outdoor factors like air pollution and weather, chemicals like pesticides and metals, and lifestyle factors like diet and exercise impacted blood pressure in kids age 6 to 11 years old. The study team focused on a total of 89 exposures in the womb and 128 exposures during early childhood. “Our results show that, starting in the fetal stage, where we live, the food we eat, the air we breathe and the chemical compounds that reach our bodies can affect blood pressure before adolescence,” said Charline Warembourg, lead author of the study and a researcher at the Barcelona Institute for Global Health (ISGlobal). “This is important because evidence shows that children with high blood pressure are more likely to be hypertensive as adults,” Warembourg said by email. Exposure to negative lifestyle factors in pregnancy, such as obesity, physical inactivity, poor diet, and alcohol and tobacco consumption have long been established as heart disease risk factors for mothers, researchers note in the Journal of the American College of Cardiology. In the current study, researchers analyzed data from blood and urine tests of young children to see what environmental, chemical and lifestyle factors might be associated with higher or lower blood pressure. https://www.reuters.com/article/us-health-childhood-hypertension/warm-weather-walkable-neighborhoods-tied-to-lower-blood-pressure-in-kids-idUSKCN1VP281

Trump Administration Awards Almost $2 Billion In Grants To Help Fight Opioid Crisis

reports that “the Trump Administration announced...it will award $1.8 billion in grant funding to state and local governments to bolster treatment and prevention efforts in the battle against the opioid epidemic.” The article says that the Substance Abuse and Mental Health Services Administration “awarded $932 million in state opioid response grants,” while the CDC “will receive $900 million over three years to improve opioid overdose tracking and other drug-related data.” https://www.usatoday.com/story/news/politics/2019/09/04/trump-offering-2-million-grants-fight-opioid-epidemic-states/2209579001/

Study Highlights E-cigarette Health Concerns

A new study published in the Journal of Clinical Investigation highlights health concerns related to the use of e-cigarettes. Using a mouse model, researchers from the Baylor College of Medicine have shown that chronic exposure to vapors from e-cigarettes can: Disrupt normal lung function Reduce the capacity of immune cells within the lungs to respond to viral infection The above changes were observed in mice exposed to vapors without nicotine, suggesting more extensive investigation may be warranted to determine the safety of solvents in e-cigarettes. "E-cigarettes currently are the most commonly consumed tobacco substitute in the adolescent population. More than 3 million high school age adolescents as well as about 10 million adults in the U.S. are active users," said corresponding author Farrah Kheradmand, in a recent press release. https://www.technologynetworks.com/drug-discovery/news/study-highlights-e-cigarette-health-concerns-323580?utm_campaign=NEWSLETTER_TN_Breaking%20Science%20News&utm_source=hs_email&utm_medium=email&utm_content=76475229&_hsenc=p2ANqtz--s3azhNviULk7N8_AyMESsSpUjmINSDBZUFhXb58mbMAyqgiNjdw7r9mlKd-KtVwOGFTdkrOGLrR9L06o223z33-ymjA&_hsmi=76475229

Wednesday, September 4, 2019

Cancer Overtakes Heart Disease As Leading Cause Of Death In Some High-Income Countries

reports research published in The Lancet indicate “cancer has overtaken heart disease as the leading cause of death in wealthy countries and could become the world’s biggest killer within just a few decades if current trends persist.” The research shows “while cardiovascular disease (CVD) remains, for now, the leading cause of mortality worldwide among middle-aged adults – accounting for 40% of all deaths – that is no longer the case in high-income countries, where cancer now kills twice as many people as heart disease.” https://www.reuters.com/article/us-health-cancer-cancer/cancer-overtakes-heart-disease-as-biggest-rich-world-killer-idUSKCN1VO0VP

Parkinson's Disease May Start in the Intestines, New Rat Study Concludes

Parkinson's disease is characterised by slowly destroying the brain due to the accumulation of the protein alpha-synuclein and the subsequent damage to nerve cells. The disease leads to shaking, muscle stiffness, and characteristic slow movements of sufferers. In the new research project, the researchers used genetically modified laboratory rats which overexpress large amounts of the alpha-synuclein protein. These rats have an increased propensity to accumulate harmful varieties of alpha-synuclein protein and to develop symptoms similar to those seen in Parkinson's patients. The researchers initiated the process by injecting alpha-synuclein into the small intestines of the rats. According to professor Per Borghammer and postdoc Nathalie Van Den Berge, the experiment was intended to demonstrate that the protein would subsequently spread in a predictable fashion to the brain. https://www.technologynetworks.com/neuroscience/news/parkinsons-disease-may-start-in-the-intestines-new-rat-study-conclude-323541?utm_campaign=NEWSLETTER_TN_Breaking%20Science%20News&utm_source=hs_email&utm_medium=email&utm_content=76420548&_hsenc=p2ANqtz-_c3x2J88tmAtDSrnQa1yobGoU_-uIpY0tGFACMsPS7Wg4Deg2n_dDyMubuqLxWmlFs2w0Adj6fcXbnhOrsbfZYO1MT3A&_hsmi=76420548

Tuesday, September 3, 2019

Blindness Caused by a Diet of Junk Food

The risks for poor cardiovascular health, obesity, and cancer associated with junk food consumption are well known, but poor nutrition can also permanently damage the nervous system, particularly vision. Nutritional optic neuropathy is a dysfunction of the optic nerve usually caused by malabsorption, drugs, or poor diet combined with alcoholism and/or smoking. It is rare in developed countries. The condition is potentially reversible if caught early. But if left untreated, it leads to permanent blindness. Researchers from Bristol Eye Hospital, Bristol, United Kingdom report the case of a 14-year-old patient who first visited his family physician complaining of tiredness. Aside from being labeled a "fussy eater," the boy had a normal BMI and took no medications. Tests showed macrocytic anemia and low vitamin B12 levels, which were treated with vitamin B12 injections and dietary advice. By age 15 years, the patient had developed sensorineural hearing loss and vision symptoms, but no cause was found. By age 17, the patient's vision had become progressively worse, to the point of blindness. The physicians investigated the patient's nutrition and found vitamin B12 deficiency, low copper and selenium levels, a high zinc level, and markedly reduced vitamin D level and bone mineral density. The patient confessed that since elementary school, he had avoided foods with certain textures and only ate French fries, Pringles, white bread, processed ham slices, and sausage. By the time his condition was diagnosed, the patient had permanently impaired vision. https://www.technologynetworks.com/applied-sciences/news/blindness-caused-by-a-diet-of-junk-food-323499?utm_campaign=NEWSLETTER_TN_Breaking%20Science%20News&utm_source=hs_email&utm_medium=email&utm_content=76369530&_hsenc=p2ANqtz-9-yyJyWAG8BAx4gPSZCVBxuL-l1ICLPjhZxEQOZ1yf9aEYmqeZVWfAbdLGMo6-XHI6XAw8eX-qFsqZcwK-j_GSv0uIrw&_hsmi=76369530

Chronic Cocaine Use Alters Gene Expression in the Mouse Hippocampus

https://www.technologynetworks.com/genomics/news/chronic-cocaine-use-alters-gene-expression-in-the-mouse-hippocampus-323509?utm_campaign=NEWSLETTER_TN_Breaking%20Science%20News&utm_source=hs_email&utm_medium=email&utm_content=76369530&_hsenc=p2ANqtz-9-yyJyWAG8BAx4gPSZCVBxuL-l1ICLPjhZxEQOZ1yf9aEYmqeZVWfAbdLGMo6-XHI6XAw8eX-qFsqZcwK-j_GSv0uIrw&_hsmi=76369530