Pertussis Vax Wanes, Even With TDaP Booster Protecting against Bordetella pertussis infection remains challenging

"We observed an abrupt shift in the direction of rate ratios in 2010, the very year that children aged 11 years would have been the first cohort born after the 1997 transition from [whole-cell] to acellular vaccines to have received acellular vaccines for all doses of the childhood series," Skoff and Martin wrote. They add that recent data show TDaP protection wanes at a faster rate among adolescents who received DTaP for their childhood vaccination as opposed to wP vaccine, and that "at least" a single dose of wP vaccine, especially when administered as the first dose, seems to improve protection associated with the TDaP vaccine. http://www.medpagetoday.com/Pediatrics/Vaccines/56988?xid=nl_mpt_DHE_2016-03-29&eun=g721819d0r