Heavy Pot Smoking Tied to Poorer Kidney Function Study found cross-sectional, but not longitudinal, association; clinical significance unknown

Heavy marijuana use was associated with poorer kidney function in young adults at the outset of an observational study, but there was no association 10 years later, a longitudinal study showed. Compared with healthy young adults who never smoked pot, those reporting daily use at the start of the study had a significantly lower mean estimated glomerular filtration rate (eGFR) (-4.5%, 95% CI -8.1 to -0.7%, P=0.02), according to Julie Ishida, MD, of the University of California San Francisco, and colleagues. Those reporting 5 or more years of cumulative marijuana use also had a significantly lower mean eGFR (-3.0%, 95% CI -5.6 to -0.4%, P=0.03), Ishida and colleagues reported in the Clinical Journal of the American Society of Nephrology. https://www.medpagetoday.com/Nephrology/GeneralNephrology/67486?xid=nl_mpt_DHE_2017-08-25&eun=g721819d0r&pos=0