Dr. House
Dr. House
Monday, April 30, 2018
MS Drug Could Reduce Painful Adverse Effects of Cancer Treatment
Researchers from the Saint Louis University School of Medicine have discovered why many multiple myeloma patients experience severe pain when treated with the anticancer drug bortezomib. The study, which will be published April 27 in the Journal of Experimental Medicine, suggests that a drug already approved to treat multiple sclerosis could mitigate this effect, allowing myeloma patients to successfully complete their treatment and relieving the pain of myeloma survivors.
Chemotherapy-induced peripheral neuropathy (CIPN) is a common, painful side effect of many anticancer drugs that can cause patients to discontinue treatment or, because symptoms can persist for years, reduce the quality of life for cancer survivors. "This growing problem is a major unmet clinical need because the increased efficacy of cancer therapy has resulted in nearly 14 million cancer survivors in the United States, many suffering from the long-term side effects of CIPN," says Daniela Salvemini, Professor of Pharmacology and Physiology at the Saint Louis University School of Medicine. https://www.technologynetworks.com/drug-discovery/news/ms-drug-could-reduce-painful-adverse-effects-of-cancer-treatment-300240?utm_campaign=Newsletter_TN_BreakingScienceNews&utm_source=hs_email&utm_medium=email&utm_content=62522460&_hsenc=p2ANqtz-_xxEuMFcEJPcaRKsAupOpoIGxoKi_-TsiiI2MT31uvNxtbWZWvt4PdzH2fqX3j7BK-V8lz0fipFmOqb5gK5tL57jQWZA&_hsmi=62522460
Frequently Heading the Ball Worse Than Concussion
“Unintentional head impacts are generally considered the most common cause of diagnosed concussions in soccer, so it’s understandable that current prevention efforts aim at minimizing those collisions,” said study leader, Michael Lipton, M.D., Ph.D., F.A.C.R., professor of radiology and of psychiatry and behavioral sciences at Einstein and medical director of MRI Services at Montefiore. “But intentional head impacts—that is, soccer ball heading—are not benign. We showed in a previous study that frequent heading is an underappreciated cause of concussion symptoms. And now we’ve found that heading appears to alter cognitive function as well, at least temporarily.” https://www.technologynetworks.com/neuroscience/news/heading-frequency-is-more-strongly-related-to-cognitive-performance-300244?utm_campaign=Newsletter_TN_BreakingScienceNews&utm_source=hs_email&utm_medium=email&utm_content=62522460&_hsenc=p2ANqtz-_xxEuMFcEJPcaRKsAupOpoIGxoKi_-TsiiI2MT31uvNxtbWZWvt4PdzH2fqX3j7BK-V8lz0fipFmOqb5gK5tL57jQWZA&_hsmi=62522460
Taxing Cookies, Candy Could Have Larger Impact On Public Health Than Taxes On Soda, Other Sugary Drinks
reported that “a large study of consumer behavior in England” suggests “taxing sweet snacks such as cookies and candy could have a greater impact on public health than taxes on soda and other sugary drinks.” The findings were published in BMJ Open. https://www.medpagetoday.com/primarycare/dietnutrition/72576
Friday, April 27, 2018
Research Looks Into Cancer Risks Among 9/11 Firefighters.
reports that “two studies published” in “JAMA Oncology suggest that the firefighters who came to lower Manhattan after the Sept. 11, 2001, attacks on the World Trade Center face a heightened risk of cancer – and will continue to do so for years to come.”
NBC News (4/26, Fox) reports on its website that “the two studies, which look only at white male firefighters, add another piece to the puzzle of what health risks are raised among 9/11 responders, but they don’t provide a definitive answer to the question.” However, “the researchers said the heavy dust of toxic chemicals that bathed just about everybody at the site, both during and in the months after the attacks, appears to be taking an especially heavy toll on first responders.”
Medscape (4/26, Mulcahy, Subscription Publication) reports that in one study, investigators found “that environmental exposure to the WTC disaster site is associated with myeloma precursor disease and ‘may be a risk factor’ for the development of multiple myeloma at an earlier age, particularly the light-chain subtype.”
HealthDay (4/26, Thompson) reports that in the other study, investigators “estimated that in the 20 years following the 9/11 terrorist attacks, an estimated 2,960 new cancer cases will develop among rescue workers who responded to Ground Zero.” The investigators found that “the rescue workers are at increased risk of prostate cancer, thyroid cancer and melanoma in particular.” http://www.latimes.com/science/sciencenow/la-sci-sn-cancer-firefighters-wtc-20180426-story.html
Working Memory Load Limit Affected by Brain Coupling, Synchrony
Working memory capacity
Maximum working memory capacity – for instance the total number of images a person can hold in working memory at the same time – varies between individuals but averages about seven. This new study tries to understand what causes the memory to have this intrinsic limit.
The study’s lead author, Dr Dimitris Pinotsis, a Lecturer at the Department of Psychology at City, University of London, and a Research Affiliate at the Department of Brain and Cognitive Sciences at MIT, said: “At peak memory capacity, the brain signals that maintain memories and guide actions based on these memories, reach their maximum. Above this peak, the same signals break down.”
As researchers have previously correlated working memory capacity with intelligence, understanding what causes working memory to have an intrinsic limit is important because it could also help explain the limited nature of conscious thought and how it might break down in diseases. https://www.technologynetworks.com/neuroscience/news/working-memory-load-limit-affected-by-brain-coupling-synchrony-300182?utm_campaign=Newsletter_TN_BreakingScienceNews&utm_source=hs_email&utm_medium=email&utm_content=62484032&_hsenc=p2ANqtz-8Yablfm-EyQI6gb4dV3q1fa7y7E4GV9NKwXfjJqPfFaqJR_61Drcar7agkJL6i8030DWqGS1rPpBlQaTHgme_E9kYnsg&_hsmi=62484032
Midday Naps Improve Teenagers' Grades
Teenagers and sleep. It’s certainly a passionate subject for many American parents … and those in China. University of Delaware’s Xiaopeng Ji is investigating the relationship between midday-napping behaviors and neurocognitive function in early adolescents. In a study funded by the National Institutes of Health, the School of Nursing assistant professor and principal investigator Jianghong Liu (University of Pennsylvania) turned to the Chinese classroom. With participants from schools in Jintan, she measured midday napping, nighttime sleep duration and sleep quality, and performance on multiple neurocognitive tasks.
Ji is interested in the relationship between sleep and cognition. Because of the intensive learning and education demands, the adolescent population is key. Neurocognitive functioning is essential for learning, emotion and behavior control. Her findings suggest that an association between habitual midday napping and neurocognitive function, especially in China, where midday napping is a cultural practice. https://www.technologynetworks.com/neuroscience/news/midday-naps-improve-teenagers-grades-300192?utm_campaign=Newsletter_TN_BreakingScienceNews&utm_source=hs_email&utm_medium=email&utm_content=62484032&_hsenc=p2ANqtz-8Yablfm-EyQI6gb4dV3q1fa7y7E4GV9NKwXfjJqPfFaqJR_61Drcar7agkJL6i8030DWqGS1rPpBlQaTHgme_E9kYnsg&_hsmi=62484032
Scleroderma and Cancer: A Mechanistic Link? Autoantibody subsets and disease phenotype may determine risk
Previous research has shown that scleroderma patients who were antipol-positive and developed cancer close to the time of their scleroderma diagnosis had mutations at the POLR3A locus, which encodes for RNA polymerase III in their tumors, "with both mutation-specific and cross-reactive immune responses seen," Shah et al noted.
"These data strongly suggest that alterations of autoantigen sequence in cancers may trigger antitumor immune responses that spread to the wild-type molecule, resulting in autoimmunity." https://www.medpagetoday.com/rheumatology/generalrheumatology/72560?xid=nl_mpt_DHE_2018-04-27&eun=g721819d0r&pos=4&utm_source=Sailthru&utm_medium=email&utm_campaign=Daily%20Headlines%202018-04-27&utm_term=Daily%20Headlines%20-%20Active%20User%20-%20180%20days
Thursday, April 26, 2018
Drinking Baking Soda: A Cheap Way to Combat Autoimmune Disease Inflammation?
They have some of the first evidence of how the cheap, over-the-counter antacid can encourage our spleen to promote instead an anti-inflammatory environment that could be therapeutic in the face of inflammatory disease, Medical College of Georgia scientists report in the Journal of Immunology.
They have shown that when rats or healthy people drink a solution of baking soda, or sodium bicarbonate, it becomes a trigger for the stomach to make more acid to digest the next meal and for little-studied mesothelial cells sitting on the spleen to tell the fist-sized organ that there's no need to mount a protective immune response. https://www.technologynetworks.com/drug-discovery/news/drinking-baking-soda-a-cheap-way-to-combat-autoimmune-disease-inflammation-300124?utm_campaign=Newsletter_TN_BreakingScienceNews&utm_source=hs_email&utm_medium=email&utm_content=62400342&_hsenc=p2ANqtz-9R5zXQKEf8F0rezV9ERITRRNT1biX_KtVay0fqAPyNMVL0_k6xFhUFbLYO8Tt92ybceiuTiajLGqJ6QZZv7WMJGQwOFg&_hsmi=62400342
Number Of Pre-Teen Mothers In The US Hits Record Low.
reports on its website that teen birth rates in the US “are at an all-time low and continue to decline,” but “the comparatively large number of teens having babies remains a concern,” according to new statistics from the Department of Health and Human Services. In 2016, there were more than 2,200 infants born to mothers aged 10-14, compared to more than 8,500 in 2000. The current rate of births to pre-teen mothers is 0.2 in 1,000 live births, and the largest decline occurred among African-American pre-teens. While this demographic still has the highest rate, 0.5 in 1,000 births, “it has been significantly reduced since 2000.” The data were compiled by the National Center for Statistics at the Centers for Disease Control. http://abcnews.go.com/Health/number-pre-teen-moms-us-record-low-cdc/story?id=54720089
Some People With Normal Fasting Glucose Results May Still Be At Higher Risk For Diabetes,
reports that “a study of participants in an employee wellness program” suggests “some people with normal fasting glucose results are still at higher risk for diabetes, and a glycated hemoglobin (HbA1c) test identified them.” Researchers found that, “compared with participants with a baseline HbA1c less than 5.7%, those with levels greater than 5.9% but less than 6.5% were more than eight times more likely to develop diabetes over 4 years of follow-up.” Participants “with levels higher than 5.7% but less than 5.9% were nearly three times as likely to develop diabetes.” The findings were published online in Diabetes Care. https://www.medpagetoday.com/endocrinology/diabetes/72542
HbA1c Level, Variability May Be Linked To Mortality Risk In Older Adults With Diabetes,
reports that research suggests “among older adults with diabetes, low and high HbA1c levels, as well as the amount of variability, were each associated with increased mortality risk.” The research was published in The Lancet Diabetes & Endocrinology. https://www.healio.com/endocrinology/diabetes/news/in-the-journals/%7B9d55ec60-dfdc-4513-8446-67f584e45027%7D/hba1c-level-variability-associated-with-mortality-risk-in-older-adults
Wednesday, April 25, 2018
Hormone Therapy With Tamoxifen Linked To Increase In Risk Of Diabetes
reports that research indicated “hormone therapy with tamoxifen was associated with a more than twofold increase in risk of diabetes, and aromatase inhibitors were associated with a more than fourfold increase.” The findings were published in the Journal of Clinical Oncology. https://www.mdedge.com/clinicalendocrinologynews/article/164092/breast-cancer/hormone-therapy-raises-diabetes-risk-breast
Eyes Might ID Preclinical Alzheimer's Presymptomatic patients show foveal thinning, retinal changes
"There's evidence that there are retinal changes in Alzheimer's disease," said lead investigator Gregory Van Stavern, MD, at the American Academy of Neurology's annual meeting.
"There's a body of literature looking at OCT metrics in patients with established Alzheimer's disease and cognitive dysfunction that shows some evidence of vascular and microvascular dysfunction in the retina."
Whether similar retinal changes occur in preclinical Alzheimer's patients was unknown. To find out, https://www.medpagetoday.com/meetingcoverage/aan/72508?xid=nl_mpt_DHE_2018-04-25&eun=g721819d0r&pos=3&utm_source=Sailthru&utm_medium=email&utm_campaign=Daily%20Headlines%202018-04-25&utm_term=Daily%20Headlines%20-%20Active%20User%20-%20180%20days
Tuesday, April 24, 2018
Kaiser Permanente Addresses Root Causes Of Childhood Obesity.
writes that 11 studies were recently published in the American Journal of Preventative Medicine that showed the results of Kaiser Permanente’s Healthy Eating Active Living initiative to combat childhood obesity. The researchers of the studies “wanted to do something about the root causes of childhood obesity and not just try to deal with the end result.” Lee says the studies “showed not only the promise but also the challenges of community interventions,” and that “real change requires coordinating multiple synergistic interventions over time.” https://www.forbes.com/forbes/welcome/?toURL=https://www.forbes.com/sites/brucelee/2018/04/23/kaiser-permanente-shows-how-to-start-tackling-the-childhood-obesity-epidemic/&refURL=&referrer=#cdc979a7f2fc
Metabolically Healthy Obesity Neither A Stable Nor Reliable Indicator Of Future CVD Risk, Research Indicates.
reports that research indicates “metabolically healthy obesity (MHO) is neither a stable nor reliable indicator of future risk for cardiovascular disease (CVD), despite having a risk similar to that of being normal weight at baseline.” Researchers found that nearly “one-half of those with MHO and no CV risk at baseline developed metabolic syndrome (MetS) during follow-up, resulting in increased odds of CVD...compared with those with stable MHO or having healthy normal weight.” The data indicated “the duration of MetS was associated with CVD in a significant and linear dose-response fashion – one visit with MetS OR 1.62, two visits OR 1.92, three or more visits OR 2.33, P value for trend <0.001 – and MetS mediated approximately 62% (44-100%) of the relationship between obesity at any point during follow-up and CVD.” The findings were published in the Journal of the American College of Cardiology. https://www.medpagetoday.com/cardiology/metabolicsyndrome/72492
Caffeine In Pregnancy Associated With Childhood Weight Gain,
reports a study from researchers at the Norwegian Institute of Public Health suggests “excessive caffeine intake during pregnancy was linked to excess growth during the infant’s first year of life and an increased risk of the child being overweight eight years later – both of which are associated with an increased risk of obesity later in life.” The findings were published in BMJ Open. https://www.cnn.com/2018/04/23/health/caffeine-pregnancy-child-overweight-study/index.html
Monday, April 23, 2018
Study Suggests Women With Osteoporosis Should Do High-Intensity Lifts.
reports on a growing movement that promotes high-intensity lifts for women with osteoporosis. A study of 101 postmenopausal women at the Bone Clinic in Brisbane found that high-intensity weight training and jumping increased lumbar-spine bone-mineral density nearly three percent over eight months, compared with a loss of 1.2 percent for a control group of women who did low-intensity workouts, the Journal says. The findings were published in the Journal of Bone and Mineral Research.
Why Zero-Calorie Sweeteners Can Still Lead to Diabetes and Obesity
The results suggest artificial sweeteners change how the body processes fat and gets its energy. In addition, they found acesulfame potassium seemed to accumulate in the blood, with higher concentrations having a more harmful effect on the cells that line blood vessels.
"We observed that in moderation, your body has the machinery to handle sugar; it is when the system is overloaded over a long period of time that this machinery breaks down," Hoffmann said. "We also observed that replacing these sugars with non-caloric artificial sweeteners leads to negative changes in fat and energy metabolism." https://www.technologynetworks.com/applied-sciences/news/why-zero-calorie-sweeteners-can-still-lead-to-diabetes-and-obesity-299941?utm_campaign=Newsletter_TN_BreakingScienceNews&utm_source=hs_email&utm_medium=email&utm_content=62296737&_hsenc=p2ANqtz--kgggUVgvKMXdP3AptzYJZMUcvg6-p9KmsZyH3P_Cz35G2DKHz0ygWl8GAwyEsFsMZJNL8mwkzF5_SX1crZ878tH8VOQ&_hsmi=62296737
Probiotics Not Only Good For Your Gu
"Probiotics have been studied most intensely in the context of the gastrointestinal tract," said Bejan Saeedi, a doctoral candidate at Emory University who conducted the research. "This study provides evidence that the effects of probiotics extend beyond the gastrointestinal tract. What makes this study unique is that it suggests a discreet molecular mechanism by which these effects are elicited."
https://www.technologynetworks.com/applied-sciences/news/probiotics-not-only-good-for-your-gut-299935?utm_campaign=Newsletter_TN_BreakingScienceNews&utm_source=hs_email&utm_medium=email&utm_content=62296737&_hsenc=p2ANqtz--kgggUVgvKMXdP3AptzYJZMUcvg6-p9KmsZyH3P_Cz35G2DKHz0ygWl8GAwyEsFsMZJNL8mwkzF5_SX1crZ878tH8VOQ&_hsmi=62296737
Friday, April 20, 2018
Opioid Prescriptions Fell 10 Percent Last Year,
reports that, according to a report from IQVIA Institute for Human Data Science released Thursday, the number of opioid prescriptions filled at retail pharmacies dropped 10 percent in 2017, “the steepest drop in the amount of painkillers dispensed to patients in 25 years.” The Post reports the trend “suggests that public outrage over the opioid epidemic and regulatory, legislative, clinical and commercial measures have begun to curb their use by physicians and patients,” but the volume of prescription opioids “has receded only to the levels of 2006 and 2007.” https://www.washingtonpost.com/
Timing Cortisol Replacement Therapy To Better Replicate Secretion Patterns Of Individuals With Normal Hormone Levels May Lead To Better Outcomes,
reports that research suggests “timing cortisol replacement therapy to better replicate the secretion patterns of individuals with normal hormone levels could result in better outcomes, with significant improvements in cognitive function.” The findings were published online in the Proceedings of the National Academy of Sciences. https://login.medscape.com/login/sso/getlogin?urlCache=aHR0cHM6Ly93d3cubWVkc2NhcGUuY29tL3ZpZXdhcnRpY2xlLzg5NTQyMg==&ac=401
BMI May Not Be Accurate Metric To Assess Obesity In Postmenopausal Women,
eports new research suggests that BMI may not be an accurate measure for classifying obesity in postmenopausal women, noting that “many older women with non-obese BMIs actually have lots of body fat.” According to researchers, “the body mass index cutoff for when people are considered obese (30) should be lower for postmenopausal women,” the article says. Researchers indicated in the journal Menopause that when using BMI, 21 percent of women were obese, but when obesity was defined by body fat, “more women fell into that category, a sign that they had been misclassified with BMI.” http://www.philly.com/philly/health/women-past-menopause-may-be-fatter-than-they-think-20180419.html
Thursday, April 19, 2018
poor muscle health may be a complication of type 1 diabetes, even in young people who get plenty of exercise.
reports that research suggests “poor muscle health may be a complication of type 1 diabetes, even in young people who get plenty of exercise.” Investigators looked at muscle samples taken from young adult patients, some of whom had type 1 diabetes and some who did not. All participants exercised more than is recommended by Diabetes Canada per week. The researchers found that “in the young adults with diabetes, the muscle biopsies revealed structural and functional changes in the ‘power plants’ (mitochondria) of cells.” The investigators found that “the mitochondria produced lower-than-normal amounts of energy and released high amounts of toxins that cause cell damage.” The findings were published in Diabetologia. https://consumer.healthday.com/diabetes-information-10/type-i-diabetes-news-182/add-muscle-weakness-as-another-cost-of-type-1-diabetes-732939.html
Altered Thyroid Function In Patients With Severe Mental Disorders May Be Partly Associated With Use Of Commonly Prescribed Antipsychotic Agents,
reports, “Patients with severe mental disorders are more likely to have altered thyroid function, which may in part be linked to the use of commonly prescribed antipsychotic agents,” research indicated. The findings of the 2,300-participant study were presented at the Schizophrenia International Research Society 2018 Biennial Meeting. https://login.medscape.com/login/sso/getlogin?urlCache=aHR0cHM6Ly93d3cubWVkc2NhcGUuY29tL3ZpZXdhcnRpY2xlLzg5NTM4Nw==&ac=401
CCTV and Microbial Swabs Showed Where Adults are Going Wrong in the Kitchen
or our latest study, we wanted to find out just where people are going wrong. But rather than conduct a survey, we decided to use the most reliable method of finding out what people are doing in the kitchen – watching them in action.
At Cardiff Metropolitan’s ZERO2FIVE Food Industry Centre, we have a fully fitted unit which is much like a home kitchen, except with CCTV cameras to observe behaviour. We wanted to explore the food safety practices of older adults in particular, so we invited 100 people over the age of 60 to prepare a meal for themselves in the unit.
Older adults are associated with increased incidence of foodborne illness, due to reduced immune function, so food safety practices at home are particularly important for them. However, researchers have found that those over 60 have insufficient knowledge, and negative attitudes towards food safety, which may contribute to the implementation of unsafe food handling practices.
But data on older adults’ actual food safety behaviours are lacking. Though there have been several studies, I have found that less than a third of consumer food safety research covering all age groups – the majority of which were conducted in home kitchens – determine actual behaviour. In home kitchens, certain variables (such as baseline microbial levels) can’t be controlled, making comparisons between individuals problematic. In addition, a researcher’s presence can make participants behave diffe
https://www.technologynetworks.com/applied-sciences/news/cctv-and-microbial-swabs-showed-where-adults-are-going-wrong-in-the-kitchen-299797?utm_campaign=Newsletter_TN_BreakingScienceNews&utm_source=hs_email&utm_medium=email&utm_content=62222883&_hsenc=p2ANqtz--XW1m9snMv0_06MlwXSX5lk1VwdVG5Hqb8BKJWBdgD2x7jN7U2dQPNPnjvgo1NNJdEZaq-7AgLZYD5TeRvN7_4ISlgbw&_hsmi=62222883
Food Crops Take Up Antimicrobials from Irrigation
sometimes can be hard to find toothpastes, soaps and other toiletries without antibiotics. Their popularity has caused an increase in environmental levels of antimicrobial substances, such as triclocarban (TCC), which end up in the water and soil used to grow crops. Scientists report in the ACS’ Journal of Agricultural and Food Chemistry that TCC and related molecules can end up in food, with potentially negative health effects.
The U.S. Food and Drug Administration recently banned TCC from soaps because of questions about its safety and efficacy. Yet, TCC remains in many other products. It’s also found in high concentrations in treated wastewater that is sometimes used to irrigate crops. The impact of TCC on human health remains unclear, but it may act as an endocrine disruptor. One obstacle to better understanding the risks of environmental TCC exposure is uncertainty about how much of it ends up in plants, and how plants metabolize the substance. So, Dawn Reinhold and colleagues undertook a study with jalapeno peppers to address this knowledge gap.
To track the antibiotic’s journey from water to pepper, the researchers labeled TCC with radioactive carbon (C14). They grew the pepper plants hydroponically and, after 12 weeks, sampled the C14 content in the roots, stems, leaves and fruit. While the pepper fruit itself had relatively low levels of TCC, it contained a hefty portion of C14 in molecules that started out as TCC but then were converted to other molecules by the plant. According to the researchers, this finding indicated that the plant was metabolizing the antibiotic, and the health impact of these metabolites would need to be taken into account to fully assess the safety of TCC consumption.
This article has been republished from materials provided by the American Chemical Society. Note: material may have been edited for length and content. For further information, please contact the cited source. https://www.technologynetworks.com/applied-sciences/news/food-crops-take-up-antimicrobials-from-irrigation-299832?utm_campaign=Newsletter_TN_BreakingScienceNews&utm_source=hs_email&utm_medium=email&utm_content=62222883&_hsenc=p2ANqtz--XW1m9snMv0_06MlwXSX5lk1VwdVG5Hqb8BKJWBdgD2x7jN7U2dQPNPnjvgo1NNJdEZaq-7AgLZYD5TeRvN7_4ISlgbw&_hsmi=62222883
Wednesday, April 18, 2018
The Immune System's Influence on Brain Development Reviewed
Complement factors – part of the immune system that kills bacteria and helps white blood cells treat infection – also shape the development of neural networks and normal brain development,” Dr Coulthard said.
“Complement factors have been linked to schizophrenia, autism spectrum disorder and non-hereditary epilepsy in genetic studies.
“Our findings mean we should be very careful when targeting the complement system to dampen inflammation during pregnancy, as there might be associated risk from treating pregnant women for inflammation.
“Either through infection or medication, complement factor activity has the potential to throw off that balance and therefore have consequences in adulthood. he findings also highlight new and unexpected potential causes for developmental brain diseases as well as risk factors for mental illness.
“Local disruption of brain development by complement factors can also result in abnormal networks, neural positions or what type of neuron the stem cell becomes,” Dr Coulthard said. https://www.technologynetworks.com/neuroscience/news/the-immune-systems-influence-on-brain-development-reviewed-299783?utm_campaign=Newsletter_TN_BreakingScienceNews&utm_source=hs_email&utm_medium=email&utm_content=62187626&_hsenc=p2ANqtz-8o6xFA1Jkm_hE9oeSEnvSlhsvOHGYmdMkaJZa7KreNZQXoCL5YuMmqm4-P44v2OKm7we_sQbmPsATPxZmMHFG6Le5B5Q&_hsmi=62187626
Dayton Confirmed case of whooping cough reported at Northmont High School
The patient WAS up to date on all of his vaccinations!
https://www.mydaytondailynews.com/news/local/confirmed-case-whooping-cough-reported-northmont-high-school/Fb6gH54Mjv9cAtYzqS7ReM/
FDA Approves Burosumab-Twza For Rare Form Of Rickets.
reports the Food and Drug Administration approved Ultragenyx Pharmaceutical Inc.’s Crysvita (burosumab-twza) “to treat x-linked hypophosphatemia in children and adults.” The FDA gave Ultragenyx a “rare pediatric disease voucher,” because the disease is “a rare and inherited form of rickets.”
Medscape (4/17, Brooks, Subscription Publication) reports Dr. Julie Beitz, the director of the FDA’s Center for Drug Evaluation and Research’s Office of Drug Evaluation III, said, “XLH differs from other forms of rickets in that vitamin D therapy is not effective. This is the first FDA-approved medication for the treatment of XLH and a real breakthrough for those living with this serious disease.” https://www.reuters.com/article/us-ultragenyx-fda/fda-approves-ultragenyxs-drug-for-rare-form-of-rickets-idUSKBN1HO2NW
With Antimalarials in Lupus, Watch for Retinal Toxicity
Antimalarials have a long history of use in lupus, Rosenbaum explained, going back at least to the 1950s, and have proved extremely valuable in treating the condition. A major study published in 2007 called LUMINA demonstrated that not only did HCQ relieve many lupus symptoms, it also had a protective effect on survival, with an odds ratio of 0.128 (95% CI 0.054 to 0.301) compared with patients not on the drug.
More recently, another study showed that combining HCQ with aspirin reduced cardiovascular events and mortality versus either drug alone and most dramatically versus neither.
How antimalarials work in lupus isn't entirely clear, but Rosenbaum listed a number of effects that likely contribute: inhibition of lysosomal enzymes and elements in the complement pathway, reductions in lipids and thrombotic factors, and spurring apoptosis of autoreactive T and B cells. The effect, he said, is to "modify the immune response without impairing normal immunity."
"Anyone who can tolerate an antimalarial should be on an antimalarial," he said flatly. https://www.medpagetoday.com/meetingcoverage/acrsota/72389?xid=nl_mpt_DHE_2018-04-18&eun=g721819d0r&pos=0&utm_source=Sailthru&utm_medium=email&utm_campaign=Daily%20Headlines%202018-04-18&utm_term=Daily%20Headlines%20-%20Active%20User%20-%20180%20days
Tuesday, April 17, 2018
Virus Causing Mononucleosis Could Be Linked To Increased Risk For Seven Other Immune System Diseases
published in Nature Genetics suggests the Epstein-Barr virus, which causes mononucleosis, could be linked to a higher risk for seven other immune system diseases: lupus, multiple sclerosis, rheumatoid arthritis, juvenile idiopathic arthritis, inflammatory bowel disease, celiac disease, and type 1 diabetes. The results “stem from an extensive genetic review of potential links between the Epstein-Barr virus and roughly 200 illnesses,” and researchers “actually uncovered preliminary links to 94 additional diseases, including breast cancer.” https://consumer.healthday.com/infectious-disease-information-21/mononucleosis-482/can-mono-virus-up-odds-for-7-other-diseases-732959.html
Researchers Find Correlation Between Testosterone Levels, Symptoms Of Postpartum Depression In New Fathers.
, psychologist Juli Fraga, PsyD, writes that even though postpartum depression “mostly affects new mothers, recent studies have found that men might also suffer from the illness.” Research published last year “in the journal Hormones and Behavior found a correlation between testosterone levels and symptoms of paternal postpartum depression.” After measuring levels of testosterone in saliva samples obtained from each father, investigators “discovered that those with dipping levels of the hormone were more likely to feel depressed.” https://www.washingtonpost.com/
Monday, April 16, 2018
Short-Term Pollution Spikes Trigger Lung Infections in Young Kids Increases in fine particulates linked to acute lower respiratory infection
Both short-term and long-term exposures to ambient air pollution have been linked to respiratory and cardiovascular diseases and death in adults, with short-term elevations in PM2.5 associated with asthma and COPD exacerbations, thrombosis, myocardial infarction, heart failure exacerbations and death. https://www.medpagetoday.com/publichealthpolicy/environmentalhealth/72328?xid=nl_mpt_DHE_2018-04-14&eun=g721819d0r&pos=0&utm_source=Sailthru&utm_medium=email&utm_campaign=Daily%20Headlines%202018-04-14&utm_term=Daily%20Headlines%20-%20Active%20User%20-%20180%20days
Taking Acetaminophen And Ibuprofen During Pregnancy May Affect Fertility Of The Unborn Child In Later Life, Tissue Study Suggests.
a study examining the effects of acetaminophen (called paracetamol in the UK) and “ibuprofen on samples of human foetal testes and ovaries” suggests that taking these medications during pregnancy may “affect the fertility of the unborn child in later life” and could “also affect the fertility of future generations, by leaving marks on DNA.” The findings were published online in Environmental Health Perspectives. reports that “ovaries exposed to paracetamol for one week had more than 40 per cent fewer egg-producing cells,” while “after ibuprofen exposure, the number of cells was almost halved.” Meanwhile, “testicular tissue exposed to painkillers in a culture dish had around a quarter fewer sperm-producing cells after exposure to paracetamol or ibuprofen.” Ovaries exposed to paracetamol for one week had more than 40 per cent fewer egg-producing cells. After ibuprofen exposure, the number of cells was almost halved.
And testicular tissue exposed to painkillers in a culture dish had around a quarter fewer sperm-producing cells after exposure to paracetamol or ibuprofen. https://www.telegraph.co.uk/news/2018/04/16/taking-paracetamol-pregnancy-may-make-grandchildren-infertile/
Night Owls May Die Younger
Being a night owl has been associated with a range of health problems. For example, night owls have higher rates of obesity, high blood pressure and cardiovascular disease. Night owls are also more likely to have unhealthy behaviors, such as smoking, alcohol and drug use, and physical inactivity. The switch to daylight saving time in the U.S. (or summer time in the U.K.) only makes things more difficult for night owls. There are higher rates of heart attacks following the switch to daylight savings, and we have to wonder if more night owls are at risk. We researchers do not fully understand why we see more health problems in night owls. It could be that being awake at night offers greater opportunity to consume alcohol and drugs. For some, being awake when everyone else is sleeping may lead to feelings of loneliness and increased risk of depression. It could also be related to our biological clocks.
As explained above, an important function of internal biological clocks is to anticipate when certain things, like sunrise, sleep and eating, will occur. Ideally, our behavior will match both our internal clock and our environment. What happens when it doesn’t? We suspect that “misalignment” between the timing of our internal clock and the timing of our behaviors could be detrimental over the long run.
A night owl trying to live in a morning lark world will struggle. Their job may require early hours, or their friends may want to have an early dinner, but they themselves prefer later times for waking, eating, socializing and sleep. This mismatch could lead to health problems in the long run. https://www.technologynetworks.com/neuroscience/articles/study-shows-night-owls-have-a-10-higher-risk-of-early-death-299688?utm_campaign=Newsletter_TN_BreakingScienceNews&utm_source=hs_email&utm_medium=email&utm_content=62116141&_hsenc=p2ANqtz-9wCloU3IhnvycQQWJ2lM4ksIX2Z3NqKW6C7-liP_l6LdouJawyU-IvqU8Fp60Hk0Mva3TKMFVIkIaswoIlK3bgvkEP7Q&_hsmi=62116141
Friday, April 13, 2018
People with ‘sweet tooth’ gene have less body fat, study says
After analyzing the results, they found that people with a gene variation of FGF21 have less body fat than others. Previous studies suggest that people with this particular gene variation crave and eat more sugary foods than others. They also noted that those with a “genetic sweet tooth” have a slightly higher hypertension risk and also more fat around the waist than hips. This body type, known as the apple shape, can increase heart attack risk, especially among women https://www.myajc.com/news/world/people-with-sweet-tooth-gene-have-less-body-fat-study-says/RnjDzD4Q4lGWyZErzMz8GK/
Researchers have designed a convenient and natural product that uses proteins to rebuild tooth enamel and treat dental cavities.
Remineralization guided by peptides is a healthy alternative to current dental health care,” said lead author Mehmet Sarikaya, professor of materials science and engineering and adjunct professor in the Department of Chemical Engineering and Department of Oral Health Sciences.
The new biogenic dental products can — in theory — rebuild teeth and cure cavities without today’s costly and uncomfortable treatments.
“Peptide-enabled formulations will be simple and would be implemented in over-the-counter or clinical products,” Sarikaya said. https://www.technologynetworks.com/proteomics/news/curing-cavities-with-peptide-products-299650?utm_campaign=Newsletter_TN_BreakingScienceNews&utm_source=hs_email&utm_medium=email&utm_content=62078379&_hsenc=p2ANqtz-8Q8Xo1QoNq0y2KeufdZiv2jh_452LQl8pER3779WJ0owv7ESO20xGBYg05mC45xizWWKtyz-XxGTjPAQGqGmuNaJRnUw&_hsmi=62078379
Why Does Drinking Alcohol or Consuming Sugar Make Us Thirsty?
We knew that exposure to alcohol or sugar turns on production of FGF21 in the liver. What we now show is that this hormone then travels in the blood to a specific part of the brain, the hypothalamus, to stimulate thirst, thereby preventing dehydration,” said Dr. Kliewer, Professor of Molecular Biology and Pharmacology and holder of the Diana K. and Richard C. Strauss Distinguished Chair in Developmental Biology. “Unexpectedly, FGF21 works through a new pathway that is independent of the classical renin-angiotensin-aldosterone thirst pathway in the kidneys.” https://www.technologynetworks.com/neuroscience/news/anti-dehydration-mechanism-discovered-299633?utm_campaign=Newsletter_TN_BreakingScienceNews&utm_source=hs_email&utm_medium=email&utm_content=62078379&_hsenc=p2ANqtz-8Q8Xo1QoNq0y2KeufdZiv2jh_452LQl8pER3779WJ0owv7ESO20xGBYg05mC45xizWWKtyz-XxGTjPAQGqGmuNaJRnUw&_hsmi=62078379
Thursday, April 12, 2018
Women Who Start Menopause Later May Have Better Verbal Recall As They Age
reports researchers found that “women who are older when they enter menopause may have a slight advantage when it comes to keeping key memory skills as they age.” The researchers found that “a woman entering menopause 10 years later than her peers was able to recall one extra word on a 15-word test for every year as she grew older.” The findings were published online in Neurology. https://consumer.healthday.com/women-s-health-information-34/menopause-and-postmenopause-news-472/could-earlier-menopause-mean-poorer-memory-in-senior-years-732847.html
Mice That Exercise When Given A Running Wheel May Begin To Move Differently When Not On The Wheel, Research Indicates.
“Well” blog reports that if a mouse is given “a running wheel, it will run,” although “it may not burn many additional calories, because it will also start to move differently when it is not on the wheel, according to” research on “the behaviors and metabolisms of exercising mice.” While this study “involved animals, but it could have cautionary implications for people who start exercising in the hopes of losing weight.” The findings were published in the journal Diabetes. https://www.nytimes.com/2018/04/11/well/move/why-exercise-alone-may-not-be-the-key-to-weight-loss.html
Fighting 'Nightmare Bacteria': Clin Onc News Report
In a recent report, the CDC discusses the discovery of an "unusual antibiotic resistant" bacteria and strategies to control its spread.
A new study reported that the factor Xa inhibitor edoxaban decreased the rate of cancer-associated venous thromboembolism compared with dalteparin.
Researchers reported that direct-acting antivirals appear to have a protective effect against liver cancer in patients with hepatitis C.
The simplified lymphatic microsurgical preventive healing approach significantly lowered the risk of lymphedema in patients undergoing axillary lymph node dissection, according to a recent analysis.
Patients with hepatitis B who take aspirin each day have a lower risk of liver cancer, new research found. https://www.medpagetoday.com/hematologyoncology/othercancers/72269?xid=nl_mpt_DHE_2018-04-12&eun=g721819d0r&pos=2&utm_source=Sailthru&utm_medium=email&utm_campaign=Daily%20Headlines%202018-04-12&utm_term=Daily%20Headlines%20-%20Active%20User%20-%20180%20days
Wednesday, April 11, 2018
Strawberries, Spinach Top List Of Produce With Most Pesticides.
reports that for the third consecutive year, “strawberries top the Environmental Working Group’s Dirty Dozen list of fruits and vegetables with the most pesticide residues.” About a third of all strawberry samples had at least ten pesticides, the article says, adding that the strawberries were followed by spinach, nectarines, apples, and grapes on the Dirty Dozen list. USA Today says the report is based on “nearly 39,000 U.S. Department of Agriculture tests of 47 fruits and vegetables,” but the Alliance for Food and Farming said the Dirty Dozen list is “unsupportable,” pointing to USDA and US Food and Drug Administration data which show 99 percent of residues are “well below safety levels” set by the Environmental Protection Agency. https://www.usatoday.com/story/news/nation-now/2018/04/10/dirty-dozen-list-fruits-vegetables-most-pesticides/502096002/
Researchers Map Variations In Death Rates, Causes Of Death Across The US.
reports the researchers used data from the Global Burden of Disease study, which is compiled from “various data sources such as the Centers for Disease Control and Prevention, the National Health and Nutrition Examination Surveys and state inpatient databases.” Dr. Christopher Murray, a professor of global health at the University of Washington and the study’s lead author, said, “There’s so many different levels of health in the US, so many different disparities across states and age groups.” Murray added, “The top five risk factors – diet, obesity, elevated blood pressure, tobacco and physical inactivity – explain an awful lot of the differences across states.” https://www.cnn.com/2018/04/10/health/states-life-expectancy-study/index.html
Researchers Develop New Device That Could Allow Blood-Free Monitoring Of Blood Sugar Levels.
reports researchers have developed a new device that “could allow people with diabetes to monitor their blood sugar levels without the need for finger sticks or other blood sampling” by instead measuring glucose in interstitial fluid. The device’s potential notwithstanding, “researchers stress that the device needs further development before it becomes a wearable, simple, blood-free way to measure blood sugar levels.” The findings were published in Nature Nanotechnology. https://www.reuters.com/article/us-health-diabetes-bloodless-monitoring/new-device-would-allow-blood-free-monitoring-of-blood-sugar-levels-idUSKBN1HH3C7
Women with PCOS Face Increased Mental Health Risks
“Polycystic ovary syndrome (PCOS) may put women at a higher risk for mental health conditions,” researchers concluded. “When compared with women without PCOS, those with the hormonal condition had a higher prevalence of several psychiatric-related conditions, including depression (23.1% versus 19.3%), anxiety (11.5% versus 9.3%), and bipolar disorder (3.2% versus 1.5%),” researchers concluded after examining data on 16,986 patients with PCOS, then matching these patients “to controls without a history of PCOS, based upon age, body mass index (BMI), and primary care practice.” The findings were published online April 10 in the Journal of Clinical Endocrinology & Metabolism. http://www.mdmag.com/medical-news/women-with-pcos-face-increased-mental-health-risks
Tuesday, April 10, 2018
Diabetes May Be Linked To Faster Degeneration Of Knee Cartilage Among Patients With OA
reports that research suggests “diabetes is associated with faster degeneration of knee cartilage among patients with osteoarthritis (OA).” The findings were published in Osteoarthritis and Cartilage. https://www.medwirenews.com/rheumatology/diabetes/diabetes-associated-with-accelerated-cartilage-deterioration/15596294
Climate Change Takes Particular Toll on At-Risk Communities
Low-income communities, people of color, and "fence-line" communities -- those located near refineries or chemical plants -- experience the health-related consequences of climate change and environmental pollution the most, according to a panelist at the Medical Society Consortium on Climate & Health at George Mason University.
For instance, when fence-line communities flood, water becomes contaminated with heavy metals, and exposure can lead to kidney damage or even renal failure, said Jewel Crawford, MD, a family physician and assistant clinical professor at the Morehouse School of Medicine in Atlanta, at the Monday meeting. https://www.medpagetoday.com/publichealthpolicy/publichealth/72231?xid=nl_mpt_DHE_2018-04-10&eun=g721819d0r&pos=2&utm_source=Sailthru&utm_medium=email&utm_campaign=Daily%20Headlines%202018-04-10&utm_term=Daily%20Headlines%20-%20Active%20User%20-%20180%20days
Monday, April 9, 2018
Higher Carotenoid Consumption May Be Linked To Reduced Risk Of Hip Fracture,
reported research suggests “Chinese adults who consume greater levels of carotenoids, including foods rich in beta-carotene, lycopene and lutein, are less likely to experience hip fracture vs. those with a diet that includes less of the antioxidants.” The findings were published in the journal Bone. https://www.healio.com/endocrinology/bone-mineral-metabolism/news/in-the-journals/%7B38a652ff-51ba-4a5d-8fe4-6829723ce856%7D/higher-carotenoid-consumption-associated-with-reduced-hip-fracture-risk
FDA Commissioner Pushing For Better Nutrition.
reported Food and Drug Administration Commissioner Scott Gottlieb “is pushing for less salt in food, more nutrition information on labels and innovative ways to communicate healthy ways of eating.” In an interview, Gottlieb said, “We spend a lot of time at the FDA on new technologies – cell and gene base therapies, regenerative medicine – that have curative potential and there is a lot of public health opportunity from what we’re seeing in the pipeline. But when you think of where we’re going to have the most dramatic public health impact, it’s going to be getting back to the public health basics, trying to sharply reduce smoking rates, trying to improve diets and trying to increase vaccination rates.” https://www.usatoday.com/story/news/politics/2018/04/06/fda-chief-scott-gottlieb-pushes-lower-sodium-better-labels-reduce-disease-obesity/493138002/
Friday, April 6, 2018
Beta-Blockers May Raise Mortality In Those With Diabetes,
reports that the “use of beta-blockers may be associated with an increased mortality risk in patients with diabetes, particularly among those who have coronary heart disease (CHD),” according to new research published in Mayo Clinic Proceedings. Medscape says, “Among nearly 3000 participants with diabetes, all-cause mortality over 5 to 6 years was significantly higher in those taking beta-blockers than those who were not, with an even more pronounced effect among those with CHD.” http://www.mayoclinicproceedings.org/article/S0025-6196(17)30845-5/fulltext
Article Describes Three Most Promising New Methods Of Male Birth Control.
reports on “several promising-products” for male birth control that “are quietly making their way through clinical trials,” including a “topical gel that blocks sperm production,” a hormonal pill contraceptive, and a “nonsurgical vasectomy.” Vox observes, “Men want more birth control options,” but the “science of finding new methods, and getting those new methods approved for market, has been incredibly difficult.” Diana Blithe, chief of the contraceptive development program at the NIH’s National Institute of Child Health and Human Development, said of the gel, “It’s the furthest along [of all male birth control methods].” Vox adds, “In a new, yet-to-be published study recently presented at the annual Endocrine Society meeting, researchers revealed data from a 100-person randomized controlled trial showing that a male birth control pill – dimethandrolone undecanoate, or DMAU – appeared to be safe when used every day for a month.” https://www.vox.com/2018/4/4/17170262/male-birth-control-explained
Thursday, April 5, 2018
Individuals With Diabetes Less Likely To See Dentist Despite Higher Risk For Gum Disease, Data Indicate.
reports that “many adults with diabetes don’t see the dentist often enough, even though” they have a higher “risk for gum disease, researchers say.” The “investigators analyzed data from just over 2.5 million American adults who took part in an annual federal government health survey.” The survey indicated “that people with diabetes or prediabetes were least likely to visit the dentist.” The findings were published online in the Journal of the American Dental Association. https://consumer.healthday.com/dental-and-oral-information-9/misc-dental-problem-news-174/those-with-diabetes-less-likely-to-see-dentist-despite-health-risks-732555.html
Taxing Products Such As Soda, Alcohol, Tobacco May Steer Consumers Toward Healthier Choices, Research Indicates.
reports a new analysis published Wednesday in The Lancet found that “taxing products such as soda, alcohol and tobacco can steer consumers toward healthier choices and avert a ruinous tumble in which obesity fuels disease and medical costs push people further into poverty, data from countries ranging from Chile to India show.” A research group examined five studies and found that taxes on unhealthy products can work without disproportionately harming the poor.
On its website, NBC News (4/4, Fox) reports that Larry Summers, a former Treasury Secretary and an emeritus professor at Harvard University, wrote commentary for the study saying, “Taxes are an underused instrument for the prevention of premature death and disease because they can discourage consumption of products like tobacco, alcohol, and sugary beverages that contribute to cardiovascular disease, cancers, diabetes, mental health problems, and injuries. Tobacco and alcohol taxes consistently raise prices, reduce consumption, and save lives, while generating additional revenues to support public services.” https://www.nbcnews.com/health/health-news/taxing-sodas-junk-food-tobacco-works-task-force-argues-n862816
Pasta May Not Be Linked To Weight Gain Or Increased Fat Levels
The researchers noted that while there are many types of pasta, they all generally have a lower GI status than other starchy foods such as white bread. The study emphasized that the inclusion of whole grains does not significantly affect pasta's GI status. And while it is relatively low in fiber, pasta has a similar GI rating to fiber-rich foods such as barley, legumes and steel cut oats, and a lower rating than wholewheat bread, breakfast cereals like bran flakes and potatoes with skin. On average, white pasta also has a higher micronutrient content than other white wheat products.
“These results are important given the negative messages with which the public has been inundated regarding carbohydrates, messages which appear to be influencing their food choices, as evidenced by recent reductions in carbohydrate intake, especially in pasta intake,” the authors wrote.
"So contrary to concerns, perhaps pasta can be part of a healthy diet such as a low GI diet,” lead author Dr John Sievenpiper, a clinician scientist with the hospital's Clinical Nutrition and Risk Modification Centre, said in a statement.
Making it whole wheat or veggie blend pasta is even better! http://www.newsweek.com/pasta-weight-loss-869178
Overweight Kids Who Lose Excess Weight In Childhood May Also Lose Higher Risk Of Type 2 Diabetes
reports that while “being overweight as a child increases the risk of type 2 diabetes in adulthood,” research published in The New England Journal of Medicine “shows that the extra risk disappears if that excess weight is lost by age 13 and kept off in early adulthood.” The study “used registry data to track weights at ages seven, 13 and in early adulthood to look for correlations to diet-dependent diabetes by age 30 to 60” in approximately 62,500 Danish men. https://www.reuters.com/article/us-health-kids-overweight/heavy-kids-who-normalize-weight-in-childhood-can-avoid-extra-diabetes-risk-idUSKCN1HB32I
Wednesday, April 4, 2018
Rare Superbugs May Be More Common Than Previously Believed
reports bacteria that carry extremely rare types of antibiotic resistance are more common in the US than previously thought, according to a report from the Centers for Disease Control and Prevention. Researchers with the Antibiotic Resistance Laboratory Network conducted nationwide testing in 2017 to identify such superbugs.
CBS News (4/3, Welch) reports on its website that the researchers found “221 instances of unusual resistance,” such as “carbapenem-resistant Enterobacteriaceae (CRE).” According to the CBS, “unusual resistance” is defined as bacteria “that cannot be killed by all or most antibiotics; are currently uncommon in the US; or have specific genes that allow them to spread their resistance to other germs.” https://www.cbsnews.com/news/antibiotic-resistant-nightmare-bacteria-a-growing-threat-in-the-u-s/
FDA Orders Kratom Recall for Salmonella Manufacturer refused to cooperate in voluntary process
Kratom is an increasingly popular herbal product, mostly imported from Southeast Asia, with opioid-like psychoactive properties. It is widely promoted for treating pain and symptoms of opioid withdrawal.
The FDA said it had asked Triangle on March 30 to initiate a recall, which the firm ignored. The agency issued another notice to Triangle the following day, ordering the company to stop distributing its kratom products. When that notice also didn't elicit a response, the agency said, on Monday it followed through with a mandatory recall order.
Other firms have complied with FDA requests to recall their kratom products, the agency said. https://www.medpagetoday.com/publichealthpolicy/publichealth/72126?xid=nl_mpt_DHE_2018-04-04&eun=g721819d0r&pos=4&utm_source=Sailthru&utm_medium=email&utm_campaign=Daily%20Headlines%202018-04-04&utm_term=Daily%20Headlines%20-%20Active%20User%20-%20180%20days
Tuesday, April 3, 2018
Hospitalization Rates For Diabetic Ketoacidosis Are On The Rise
reports that CDC data indicate that “hospitalization rates for diabetic ketoacidosis (DKA) are on the rise.” Following “a nearly 10-year period of slight decline, age-adjusted rates of hospitalization for the life-threatening, preventable diabetes complication increased nearly 55% between 2009 and 2014.” The findings were published in the CDC’s Morbidity and Mortality Weekly Report. https://login.medscape.com/login/sso/getlogin?urlCache=aHR0cHM6Ly93d3cubWVkc2NhcGUuY29tL3ZpZXdhcnRpY2xlLzg5NDY3Mg==&ac=401
Monday, April 2, 2018
New Diabetes Subgroups May Improve Treatment Outcomes,
reported that “clustering patients into 5 subgroups may be beneficial for identifying those at risk for diabetic complications,” according to a study published in the Lancet Diabetes & Endocrinology. The investigators wrote, “the results of our study suggest that this new clustering of patients with adult-onset diabetes is superior to the classic diabetes classification because it identifies patients at high risk of diabetic complications at diagnosis and provides information about underlying disease mechanisms, thereby guiding choice of therapy.” https://www.endocrinologyadvisor.com/type-2-diabetes-advisor/diabetes-subgroups-novel-treatment-prevention-diabetic-complications/article/753602/
“Hospital-At-Home” Care Helps Some Patients Avoid “Germy And Noisy” Hospitals.
reported on “hospital-at-home” scenarios where physicians and nurses come to patients’ home twice a day and perform any needed tests or bloodwork to help patients avoid “germy and noisy” hospitals and reduce labor costs. A wireless patch can be affixed to a patient’s skin to track vital signs and send a steady stream of data to the hospital. While such systems have been in place in other countries, “a key obstacle” in the US is getting health insurers to pay for it. https://www.washingtonpost.com/national/health-science/hospitals-are-germy-noisy-places-some-acutely-ill-patients-are-getting-treated-at-home-instead/2018/03/30/5fcb5006-2155-11e8-badd-7c9f29a55815_story.html
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