Gut Bacteria Recover after Antibiotics... Nearly

https://www.technologynetworks.com/tn/news/gut-bacteria-recover-after-antibiotics-nearly-311010?utm_campaign=Newsletter_TN_BreakingScienceNews&utm_source=hs_email&utm_medium=email&utm_content=66969030&_hsenc=p2ANqtz-8ZPiGkV8OqH9MOgGSUsBxXkxJRY04YWXys1jtG7XZMKwUY3ZLayjTFAJR-_k7lT2aK1L7tkEOSbAtpbKODCtZ2XT1Adg&_hsmi=66969030 The use of antibiotics has long been linked to deprivation of gut bacteria. Now, a new study from University of Copenhagen shows that the composition and function of gut bacteria can recover after antibiotic treatment in healthy people. But after six months, the gut still lack nine common beneficial bacterial species. The trillions of bacteria in the human gut affect our health in multiple ways including effects on immune functions and metabolism. A rich and diverse gut microbiota is considered to promote health providing the human host with many competences to prevent chronic diseases. In contrast, poor diversity of the gut ecosystem is a characteristic feature of chronic diseases including obesity, diabetes, asthma and gut inflammatory disorders. Due the general bacterial-killing nature of antibiotics, it has been speculated that repetitive use of antibiotics deprives people of a rich gut bacterial environment and through this lead to adverse health effects. Now, an international team of researchers led from the University of Copenhagen and Steno Diabetes Center Copenhagen report when 3 antibiotics were given to young healthy men for 4 days it caused an almost complete eradication of gut bacteria, followed by a gradual recovery of most bacterial species over a period of six months. After the six months, however, the study participants were still missing nine of their common beneficial bacteria and a few new potentially non-desirable bacteria had colonized the gut. The findings are published today in Nature Microbiology. “We show that the gut bacterial community of healthy adults are resilient and able to recover after short-term simultaneous exposure to three different antibiotics However, our findings also suggest that exposure to broad-spectrum antibiotics may dilute the diversity of the intestinal bacterial ecosystem. Antibiotics can be a blessing for preserving human health but should only be used based upon clear evidence for a bacterial cause of infection,” explains study lead , Professor Oluf Pedersen, Novo Nordisk Foundation Center for Basic Metabolic Research.