Maternal Low-Grade Systemic Inflammation During Second Trimester Of Pregnancy May Be Tied To Higher Risk For Childhood Overall And Central Adiposity.

“We observed that a higher maternal [C-reactive protein] level in the second trimester was associated with increased total body fat mass and truncal fat mass in the offspring,” Romy Gaillard, MSc, PhD, a postdoctoral researcher and MD student at Erasmus Medical Center in Rotterdam, Netherlands, and colleagues wrote. “These associations were independent of maternal prepregnancy BMI and not explained by the development of maternal pregnancy complications, including gestational diabetes and gestational hypertensive disorders, or gestational age and weight at birth.” http://www.healio.com/endocrinology/obesity/news/online/%7Bde7b672e-6bbe-4c33-8971-52b0b0309de7%7D/maternal-inflammation-in-pregnancy-associated-with-childhood-adiposity