Fat Cells In Obese People Behave Differently Than In Healthy Weight People, Study Suggests.

While insulin changed levels of gene expression in over 200 genes in both groups of obese participants, it affected the expression just two genes in the non-obese group. Gene expression can change the proteins a cell has to work with — so these findings indicate that fat cells in obese people are doing something different than fat cells in healthy people, said Dr. Mikael Rydén, an endocrinologist at the Karolinska Institute in Sweden and lead researcher in the study. Based on your ability to consume oxygen during maximal exercise, you can be obese and be fitter than someone who’s lean. And if you are fat but fit you have a lower risk of heart disease and diabetes than if you’re lean and unfit.” The study also only looked at fat cells, Rydén pointed out. It doesn’t tell us how insulin might affect the function of other tissues, like kidneys and livers. BIG QUESTION Did obesity cause gene differences, or did the gene differences cause obesity??? https://www.statnews.com/2016/08/18/fat-but-fit/