Alternate-Day Fasting Doesn't Lead to Speedier Weight Loss Approach not superior to calorie-restrictive diet

Alternate-day fasting was not superior to a calorie-restrictive diet for weight loss, weight maintenance, or cardioprotection, according to trial results. There were no significant differences in mean weight loss between the alternate-day fasting group versus the calorie restriction group after 6 months of intervention, relative to the control group: -6.8% (95% CI -9.1% to -4.5%) versus -6.8 (95% CI -9.1% to -4.6%), reported Krista A. Varady, PhD, of the University of Illinois at Chicago, and colleagues. Findings were consistent when the groups were followed through a year, after a 6-month maintenance phase: -6.0% (95% CI -8.5% to -3.6%) versus -5.3% (95% CI -7.6% to -3.0%), they wrote in JAMA Internal Medicine. During the year-long, randomized clinical trial, the two intervention groups experienced no significant differences among secondary endpoints, which included blood pressure, heart rates, triglycerides, fasting glucose, fasting insulin, insulin resistance, C-reactive protein, and homocysteine concentrations. https://www.medpagetoday.com/Endocrinology/Obesity/64928?xid=nl_mpt_DHE_2017-05-02&eun=g721819d0r&pos=0