In Patients At High Genetic Risk For T2D Exercise May Have Smaller Protective Effect.

reports that, according to a study funded by the National Institutes of Health and published in the journal Diabetologia, “individuals with a relatively large number of genetic factors linked to type 2 diabetes [T2D] risk showed a smaller protective effect of exercise.” The study, which examined data on 8,101 patients found that “when participants were stratified by genetic risk (defined as the presence of single nucleotide polymorphisms [SNPs]) there was little difference in incidence rates for new-onset type 2 diabetes in those with high versus low levels of physical activity.” Conversely, “those with low genetic risk scores were half as likely to develop type 2 diabetes when their physical activity was rated as high versus low,” the study found. http://www.medpagetoday.com/Endocrinology/Diabetes/47883