Physicians Debate How Low To Go With LDL Cholesterol In Patients With Diabetes.

reports that at ENDO 2018: The Endocrine Society Annual Meeting, Steve Nissen, MD, and Henry N Ginsberg, MD, debated “the benefits of ultra-low, low-density lipoprotein (LDL) cholesterol versus a more reasonable, but still low, level among patients with diabetes.” Dr. Nissen “claims that LDL levels of 25 mg/dL ‘are good,’ and in the IMPROVE-IT trial with ezetimibe...levels were driven as low as 15 mg/dL ‘and we saw massive regression of atherosclerosis.’” However, Dr. Ginsberg “maintained that the biggest benefit in LDL lowering is seen when patients with very high levels get down to moderate levels – even, for example, dropping from 200 to 100 mg/dL, as seen in the 4S trial.”